Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21495061 | 0.86 | CES2 (0.38) | ERN1 | |
| SCHEMBL4709591 | 0.86 | CES2 (0.38) | ERN1 | |
| SCHEMBL21724409 | 0.86 | TSHR (0.38) | ERN1 | |
| SCHEMBL7356689 | 0.74 | RXRA (0.33) | — | |
| SCHEMBL1701138 | 0.72 | MDM2 (0.40) | MDM2 | |
| SCHEMBL1515887 | 0.72 | TRPM8 (0.42) | TRPM8 | |
| SCHEMBL6992997 | 0.71 | CES2 (0.39) | — | |
| SCHEMBL19137058 | 0.71 | ALDH1A1 (0.33) | TRPM8 | |
| SCHEMBL167914 | 0.71 | HDAC4 (0.44) | — | |
| SCHEMBL169020 | 0.71 | ACP3 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |