Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18530070 | 0.83 | ALDH1A1 (0.43) | PTGS2ALDH1A1KDM4EHPGDL3MBTL1 | |
| SCHEMBL28999742 | 0.83 | PTGS2 (0.43) | PTGS2ALDH1A1TSHRNQO2SLC6A3 | |
| SCHEMBL18713910 | 0.82 | SMN1; SMN2 (0.40) | PTGS2ALDH1A1KDM4EHPGDL3MBTL1 | |
| SCHEMBL4651083 | 0.82 | SMN1; SMN2 (0.40) | PTGS2ALDH1A1KDM4EHPGDL3MBTL1 | |
| SCHEMBL2886215 | 0.80 | HPGD (0.49) | ALDH1A1KDM4EHPGDMAPTNPSR1 | |
| SCHEMBL30762808 | 0.73 | CA1 (0.37) | ALDH1A1L3MBTL1MAPTTSHRPOLB | |
| SCHEMBL18529143 | 0.69 | FPR2 (0.35) | PTGS2ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL18543665 | 0.67 | CYP19A1 (0.39) | PTGS2ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL30762781 | 0.67 | HCAR2 (0.38) | ALDH1A1L3MBTL1MAPTTSHRHSD11B1 | |
| SCHEMBL18529189 | 0.67 | HCAR2 (0.38) | ALDH1A1L3MBTL1MAPTTSHRHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107848968-B | Process for preparing lactams from glyoxylic acid | 荷兰联合利华有限公司 | 2021-06-18 | — | — | CN | disclosed |
| EP-3337785-B1 | PROCESS FOR THE PREPARATION OF LACTAMS FROM GLYOXYLIC ACID | UNILEVER PLC (GB) | 2020-03-18 | — | — | EP | disclosed |
| EP-3337785-B1 | PROCESS FOR THE PREPARATION OF LACTAMS FROM GLYOXYLIC ACID | UNILEVER PLC (GB) | 2020-03-18 | — | — | EP | disclosed |
| US-10377707-B2 | Process for the preparation of lactams from glyoxalic acid | CONOPCO INC. (US) | 2019-08-13 | — | — | US | disclosed |
| US-10377707-B2 | Process for the preparation of lactams from glyoxalic acid | CONOPCO INC. (US) | 2019-08-13 | — | — | US | disclosed |
| US-20180237388-A1 | PROCESS FOR THE PREPARATION OF LACTAMS FROM GLYCOXYLIC ACID | Conopco, Inc., a/b/a UNILEVER (US) | 2018-08-23 | — | — | US | disclosed |
| EP-3337785-A1 | PROCESS FOR THE PREPARATION OF LACTAMS FROM GLYOXYLIC ACID | Unilever PLC (GB) | 2018-06-27 | — | — | EP | disclosed |
| WO-2017029104-A1 | PROCESS FOR THE PREPARATION OF LACTAMS FROM GLYOXYLIC ACID | UNILEVER PLC (GB) | 2017-02-23 | — | — | WO | disclosed |
| WO-2017029104-A1 | PROCESS FOR THE PREPARATION OF LACTAMS FROM GLYOXYLIC ACID | UNILEVER PLC (GB) | 2017-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10377707-B2 | Process for the preparation of lactams from glyoxalic acid | GLO1, PGLS, GRHPR | PTGS2 929/4885ALDH1A1 2836/4885LMNA 1198/4885 |
| US-20180237388-A1 | PROCESS FOR THE PREPARATION OF LACTAMS FROM GLYCOXYLIC ACID | PGLS, MGAM, GLA | PTGS2 1875/4885ALDH1A1 3248/4885LMNA 935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.