Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 2/20 | 0.47 |
| ▸ | ATF1 | P18846 | 5/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.39 |
| ▸ | TUBB | P07437 | 2/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29663634 | 0.80 | TUBB4A (0.43) | MLYCDTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3700292 | 0.80 | TUBB4A (0.43) | MLYCDTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL18529452 | 0.80 | LIPE (0.43) | ATF1NFKB1MEN1KMT2AGAA | |
| SCHEMBL30751960 | 0.79 | XPO1 (0.55) | XPO1ATF1NFKB1TUBB4ATUBB | |
| SCHEMBL28830749 | 0.79 | XPO1 (0.55) | XPO1ATF1NFKB1TUBB4ATUBB | |
| SCHEMBL26179779 | 0.79 | TUBB4A (0.42) | NFKB1MLYCDTUBB4ATUBBTUBA3C | |
| SCHEMBL20808527 | 0.78 | XPO1 (0.60) | XPO1ATF1NFKB1MEN1KMT2A | |
| SCHEMBL3834955 | 0.78 | TUBB4A (0.41) | MLYCDTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3778708 | 0.77 | TUBB4A (0.46) | MLYCDTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL20303639 | 0.77 | MLYCD (0.40) | XPO1MLYCDTUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137538-B | Triazole derivatives, intermediates thereof and their use as fungicides | 拜耳作物科学股份公司 | 2021-02-26 | — | — | CN | disclosed |
| US-20200095223-A1 | NOVEL TRIAZOLETHIONE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-03-26 | — | — | US | disclosed |
| US-20200095223-A1 | NOVEL TRIAZOLETHIONE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-03-26 | — | — | US | disclosed |
| US-20200045967-A1 | NOVEL TRIAZOLE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-13 | — | — | US | disclosed |
| US-20200045967-A1 | NOVEL TRIAZOLE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-13 | — | — | US | disclosed |
| US-20200029563-A1 | NOVEL 5-SUBSTITUTED IMIDAZOLYLMETHYLDIOXOLANE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2020-01-30 | — | — | US | disclosed |
| US-20200029563-A1 | NOVEL 5-SUBSTITUTED IMIDAZOLYLMETHYLDIOXOLANE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2020-01-30 | — | — | US | disclosed |
| EP-3519404-A1 | 5-SUBSTITUTED IMIDAZOLYLMETHYLDIOXOLANE DERIVATIVES AS FUNGICIIDES | Bayer CropScience Aktiengesellschaft (DE) | 2019-08-07 | — | — | EP | disclosed |
| US-20180235223-A1 | TRIAZOLE DERIVATIVES, INTERMEDIATES THEREOF AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-08-23 | — | — | US | disclosed |
| WO-2018145933-A1 | TRIAZOLETHIONE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2018-08-16 | — | — | WO | disclosed |
| WO-2018145921-A1 | COMPOSITION FOR CONTROLLING HARMFUL MICROORGANISMS COMPRISING 1 -(PHENOXY-PYRIDINYL)-2-(1,2,4-TRIAZOL-1 -YL)-ETHANOL DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2018-08-16 | — | — | WO | disclosed |
| EP-3334718-A1 | TRIAZOLE DERIVATIVES, INTERMEDIATES THEREOF AND THEIR USE AS FUNGICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2018-06-20 | — | — | EP | disclosed |
| WO-2018060088-A1 | 5-SUBSTITUTED IMIDAZOLYLMETHYLDIOXOLANE DERIVATIVES AS FUNGICIIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-04-05 | — | — | WO | disclosed |
| WO-2017029179-A1 | TRIAZOLE DERIVATIVES, INTERMEDIATES THEREOF AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-02-23 | — | — | WO | disclosed |
| WO-2017029179-A1 | TRIAZOLE DERIVATIVES, INTERMEDIATES THEREOF AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180235223-A1 | TRIAZOLE DERIVATIVES, INTERMEDIATES THEREOF AND THEIR USE AS FUNGICIDES | CYP51A1, ERG28, CYP4Z1 | XPO1 2356/4885ATF1 1980/4885NFKB1 2827/4885 |
| US-20200045967-A1 | NOVEL TRIAZOLE DERIVATIVES | CYP51A1, ERG28, SBK3 | XPO1 2888/4885ATF1 447/4885NFKB1 1004/4885 |
| US-20200095223-A1 | NOVEL TRIAZOLETHIONE DERIVATIVES | CYP51A1, SBK3, TST | XPO1 2665/4885ATF1 270/4885NFKB1 1834/4885 |
| US-20200029563-A1 | NOVEL 5-SUBSTITUTED IMIDAZOLYLMETHYLDIOXOLANE DERIVATIVES | PIP5K1B, PIP5K1A, PIP5K1C | XPO1 2806/4885ATF1 717/4885NFKB1 471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.