Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16408356 | 0.86 | LTA4H (0.49) | LTA4HMAPTSMN1; SMN2KMT2ACRBN | |
| SCHEMBL18872085 | 0.82 | CRBN (0.57) | LTA4HMAPTALOX15KMT2ACRBN | |
| SCHEMBL24910640 | 0.75 | LMNA (0.53) | MAPTSMN1; SMN2KMT2AHTTHSP90AA1 | |
| SCHEMBL29933509 | 0.75 | SMN1; SMN2 (0.59) | MAPTSMN1; SMN2ALOX15KMT2AMEN1 | |
| SCHEMBL18530849 | 0.75 | SMN1; SMN2 (0.59) | MAPTSMN1; SMN2ALOX15KMT2AMEN1 | |
| SCHEMBL21758465 | 0.73 | NR4A2 (0.55) | HTT | |
| SCHEMBL7872416 | 0.73 | CPS1 (0.57) | MAPTKMT2AHTTHSP90AA1MEN1 | |
| SCHEMBL15447330 | 0.71 | MAPT (0.53) | MAPTSMN1; SMN2ALOX15KMT2AMEN1 | |
| SCHEMBL31704211 | 0.69 | POLB (0.46) | LTA4HMAPTKMT2AMEN1NPC1 | |
| SCHEMBL13071791 | 0.69 | ALDH1A1 (0.41) | LTA4HCRBNPOLBTSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9573957-B2 | Inhibitors of leukotriene production | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-02-21 | — | — | US | disclosed |