SCHEMBL18535

SCHEMBL18535

N#Cc1nccc(-c2cccc(C(F)(F)F)c2)n1

nearest known ligand 0.63

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CTSS P25774 8/20 0.63
CTSK P43235 16/20 0.60
KMO O15229 2/20 0.58
KCNH2 Q12809 10/20 0.57
CTSB P07858 3/20 0.52
CTSL P07711 2/20 0.52
IRAK4 Q9NWZ3 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL27908901 0.91 KMO (0.62) CTSSCTSKKMOKCNH2CTSB
SCHEMBL18157 0.82 KMO (0.55) CTSSCTSKKMOKCNH2IRAK4
SCHEMBL9792898 0.79 KMO (0.59) CTSSCTSKKMOIRAK4
SCHEMBL3873916 0.79 CTSK (0.65) CTSSCTSKKCNH2CTSBCTSL
SCHEMBL3881727 0.79 CTSK (0.66) CTSSCTSKKCNH2CTSBCTSL
SCHEMBL28924400 0.78 CTSS (0.57) CTSSCTSKKMOKCNH2CTSB
SCHEMBL30081919 0.78 CTSS (0.57) CTSSCTSKKMOKCNH2CTSB
SCHEMBL2788482 0.78 CCNT1 (0.63) CTSSKMO
SCHEMBL11469890 0.78 KMO (0.62) CTSSCTSKKMO
SCHEMBL9954071 0.78 CTSS (1.00) CTSSCTSKKMOKCNH2CTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012025460-A1 OXADIAZOLINONE DERIVATIVES AND USE THEREOF IN PEST CONTROL BAYER CROPSCIENCE AG (DE) 2012-03-01 WO disclosed