Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 5/20 | 0.57 |
| ▸ | KMO | O15229 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 9/20 | 0.50 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30081919 | 1.00 | CTSS (0.57) | CTSSKMOKDM4ECTSKTGFBR1 | |
| SCHEMBL893514 | 0.83 | KIF11 (0.56) | CTSSCTSKTGFBR1KCNH2 | |
| SCHEMBL9792939 | 0.82 | CLK4 (0.62) | IDO1GRM5CLK4 | |
| SCHEMBL17116600 | 0.81 | CLK4 (0.51) | IDO1GRM5CLK4 | |
| SCHEMBL6236184 | 0.79 | CTSS (0.57) | CTSSKMOKDM4ECTSKKCNH2 | |
| SCHEMBL3836507 | 0.79 | CTSS (0.55) | CTSSKDM4ECTSKGRIN1GRIN2B | |
| SCHEMBL18535 | 0.78 | CTSS (0.63) | CTSSKMOCTSKKCNH2CTSL | |
| SCHEMBL30158989 | 0.77 | ASIC3 (0.53) | TGFBR1GRM5CLK4 | |
| SCHEMBL2949191 | 0.77 | ASIC3 (0.53) | TGFBR1GRM5CLK4 | |
| SCHEMBL13692259 | 0.77 | ABL1 (0.58) | CTSSKMOKDM4ETGFBR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403519-B | Synthesis method of N-substituted isonicotinamide compound driven by visible light | 河南师范大学 | 2024-03-01 | — | — | CN | disclosed |
| CN-115403519-A | Synthesis method of N-substituted isonicotinamide compound driven by visible light | 河南师范大学 | 2022-11-29 | — | — | CN | disclosed |