Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | ACHE | P22303 | 2/20 | 0.55 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 7/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23713525 | 0.89 | GLA (0.54) | NPC1RAB9AMAOBKDM4EALDH1A1 | |
| SCHEMBL18535678 | 0.89 | NPC1 (0.51) | NPC1RAB9AACHEGPR55MAOB | |
| SCHEMBL23713548 | 0.88 | NPC1 (0.50) | NPC1RAB9AACHEGPR55MAOB | |
| SCHEMBL24046235 | 0.87 | NPC1 (0.43) | NPC1RAB9AACHEGPR55MAOB | |
| SCHEMBL18535466 | 0.86 | GPR55 (0.44) | NPC1RAB9AACHEGPR55MAOB | |
| SCHEMBL18554418 | 0.86 | MAOB (0.57) | NPC1RAB9AACHEGPR55MAOB | |
| SCHEMBL18554377 | 0.86 | NPC1 (0.51) | NPC1RAB9AACHEGPR55MAOB | |
| SCHEMBL23713526 | 0.86 | NPC1 (0.42) | NPC1RAB9AACHEGPR55MAOB | |
| SCHEMBL18583399 | 0.83 | MAOB (0.57) | NPC1RAB9AACHEGPR55MAOB | |
| SCHEMBL18535562 | 0.82 | MEN1 (0.57) | NPC1RAB9AKDM4EALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11702396-B2 | Hydrophobic compounds for optically active devices | Johnson & Johnson Surgical Vision, Inc. (US) | 2023-07-18 | — | — | US | disclosed |
| US-11702396-B2 | Hydrophobic compounds for optically active devices | Johnson & Johnson Surgical Vision, Inc. (US) | 2023-07-18 | — | — | US | disclosed |
| US-20210363122-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2021-11-25 | — | — | US | disclosed |
| US-11078177-B2 | Compounds for optically active devices | MERCK PATENT GMBH (DE) | 2021-08-03 | — | — | US | disclosed |
| US-11001576-B2 | Compounds for optically active devices | MERCK PATENT GMBH (DE) | 2021-05-11 | — | — | US | disclosed |
| EP-3583102-B1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |
| EP-3583101-B1 | BIS-COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-10-28 | — | — | EP | disclosed |
| US-20200062739-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-02-27 | — | — | US | disclosed |
| US-10457658-B2 | Compounds for optically active devices | MERCK PATENT GMBH (DE) | 2019-10-29 | — | — | US | disclosed |
| WO-2017032442-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2017-03-02 | — | — | WO | disclosed |
| EP-3133065-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | Merck Patent GmbH (DE) | 2017-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210363122-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | PDE6C, ALDH1A2, PDE6A | NPC1 2482/4885RAB9A 930/4885ACHE 112/4885 |
| US-11702396-B2 | Hydrophobic compounds for optically active devices | UACA, CRYZ, TRPA1 | NPC1 1051/4885RAB9A 1916/4885ACHE 895/4885 |
| US-10457658-B2 | Compounds for optically active devices | PDE6C, ALDH1A2, PDE6A | NPC1 2482/4885RAB9A 930/4885ACHE 112/4885 |
| US-20200062739-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | PDE6C, PDE6A, PDE6D | NPC1 2727/4885RAB9A 1119/4885ACHE 70/4885 |
| US-11078177-B2 | Compounds for optically active devices | PDE6C, ALDH1A2, PDE6A | NPC1 2482/4885RAB9A 930/4885ACHE 112/4885 |
| US-11001576-B2 | Compounds for optically active devices | PDE6C, PDE6A, PDE6D | NPC1 2727/4885RAB9A 1119/4885ACHE 70/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.