Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6245968 | 0.88 | NOS3 (0.33) | ALDH1A1NOS3NOS1NOS2ENPEP | |
| SCHEMBL1852682 | 0.88 | NOS3 (0.33) | ALDH1A1NOS3NOS1NOS2ENPEP | |
| Methane SCHEMBL30958396 | 0.86 | ALDH1A1 (0.40) | ALDH1A1NOS3NOS1NOS2ENPEP | |
| SCHEMBL6665323 | 0.85 | ALDH1A1 (0.35) | ALDH1A1NOS3NOS1NOS2ENPEP | |
| SCHEMBL6670962 | 0.84 | GABRP (0.41) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL790160 | 0.78 | MEN1 (0.33) | — | |
| SCHEMBL1025240 | 0.77 | — | — | |
| SCHEMBL18490871 | 0.77 | GABRP (0.43) | ALDH1A1 | |
| SCHEMBL4247232 | 0.77 | GABRP (0.43) | ALDH1A1 | |
| SCHEMBL360638 | 0.76 | GPR84 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697400-B1 | BIPHENYL-SUBSTITUTED ANTIBACTERIAL MACROCYCLES | AICURIS GMBH & CO KG (DE) | 2011-05-25 | — | — | EP | disclosed |
| WO-2005118613-A2 | ANTIBACTERIAL AMIDE MACROCYCLES | AICURIS GMBH & CO.KG (DE) | 2005-12-15 | — | — | WO | disclosed |