Methane

Methane

SCHEMBL30958396

C.CC(C)(C)N(CCCCC(N)CCCCN(C(=O)O)C(C)(C)C)C(=O)O

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
ENPEP Q07075 3/20 0.34
S1PR2 O95136 5/20 0.32
S1PR1 P21453 5/20 0.32
S1PR3 Q99500 5/20 0.32
S1PR4 O95977 4/20 0.32
GRIK1 P39086 2/20 0.32
GRIK2 Q13002 2/20 0.32
SLC1A2 P43004 1/20 0.32
SLC1A1 P43005 1/20 0.32
PLA2G1B P04054 1/20 0.31
PLA2G2A P14555 1/20 0.31
NOS3 P29474 1/20 0.30
NOS1 P29475 1/20 0.30
NOS2 P35228 1/20 0.30
ACACB O00763 1/20 0.30
ACACA Q13085 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1853569 0.86 ALDH1A1 (0.34) ALDH1A1ENPEPNOS3NOS1NOS2
SCHEMBL6245968 0.84 NOS3 (0.33) ALDH1A1ENPEPNOS3NOS1NOS2
SCHEMBL6665323 0.84 ALDH1A1 (0.35) ALDH1A1ENPEPGRIK1GRIK2SLC1A2
SCHEMBL1852682 0.84 NOS3 (0.33) ALDH1A1ENPEPNOS3NOS1NOS2
SCHEMBL17165537 0.82 PLA2G1B (0.34) PLA2G1BPLA2G2A
SCHEMBL17165535 0.82 PLA2G1B (0.34) PLA2G1BPLA2G2A
SCHEMBL2495115 0.80 NOS2 (0.36) GRIK1GRIK2SLC1A2SLC1A1NOS3
SCHEMBL6670962 0.80 GABRP (0.41) ALDH1A1SLC1A2SLC1A1NOS3NOS1
SCHEMBL838138 0.77 CHRM2 (0.38) ALDH1A1
SCHEMBL1025240 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024094098-A1 COMPOUND FOR DELIVERY SYSTEM AND USE THEREOF 益杰立科(上海)生物科技有限公司 2024-05-10 WO disclosed