Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.31 |
| ▸ | ENPEP | Q07075 | 3/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.30 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5437634 | 0.89 | CA2 (0.31) | ALDH1A1CA2MAPK1SLC1A2SLC1A1 | |
| SCHEMBL6245968 | 0.86 | NOS3 (0.33) | ALDH1A1NOS3NOS1NOS2ENPEP | |
| SCHEMBL1852682 | 0.86 | NOS3 (0.33) | ALDH1A1NOS3NOS1NOS2ENPEP | |
| SCHEMBL1853569 | 0.85 | ALDH1A1 (0.34) | ALDH1A1NOS3NOS1NOS2ENPEP | |
| Methane SCHEMBL30958396 | 0.84 | ALDH1A1 (0.40) | ALDH1A1NOS3NOS1NOS2SLC1A2 | |
| SCHEMBL6670962 | 0.82 | GABRP (0.41) | ALDH1A1NOS3NOS1NOS2SLC1A2 | |
| SCHEMBL2520169 | 0.77 | — | — | |
| SCHEMBL5452669 | 0.77 | — | — | |
| SCHEMBL2517593 | 0.76 | — | — | |
| SCHEMBL10830752 | 0.75 | CA12 (0.40) | ALDH1A1CA2MAPK1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1457483-A1 | Cationic lipids with serine backbone | Ruhr-Universität Bochum (DE) | 2004-09-15 | — | — | EP | disclosed |