Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 14/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL185644 | 0.87 | CTSA (0.42) | CTSAALDH1A1 | |
| SCHEMBL22457063 | 0.79 | JAK2 (0.43) | ALDH1A1HPGD | |
| SCHEMBL186238 | 0.77 | LMNA (0.61) | ALDH1A1HPGD | |
| SCHEMBL7723692 | 0.77 | ALDH1A1 (0.46) | ALDH1A1HPGD | |
| SCHEMBL186416 | 0.77 | LMNA (0.61) | ALDH1A1HPGD | |
| SCHEMBL186230 | 0.77 | LMNA (0.61) | ALDH1A1HPGD | |
| SCHEMBL8286102 | 0.76 | ESR1 (0.43) | CTSA | |
| SCHEMBL14220105 | 0.74 | ALOX15 (0.43) | ALDH1A1HPGD | |
| SCHEMBL4319856 | 0.74 | L3MBTL1 (0.39) | CTSAALDH1A1 | |
| SCHEMBL16371412 | 0.74 | ALDH1A1 (0.43) | CTSAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401260-A1 | DIOXO-IMIDAZOLIDINE DERIVATIVES, WHICH INHIBIT THE ENZYME SOAT-1, AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM | Galderma Research & Development (FR) | 2012-01-04 | — | — | EP | claimed |
| WO-2010097465-A1 | DIOXO-IMIDAZOLIDINE DERIVATIVES, WHICH INHIBIT THE ENZYME SOAT-1, AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-09-02 | — | — | WO | claimed |