Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45199 | 0.85 | MEN1 (0.41) | ALDH1A1ALOX15MAPK1MEN1KMT2A | |
| SCHEMBL756324 | 0.78 | PDE2A (0.50) | CYP2A6ALDH1A1CA1CA2CA5A | |
| SCHEMBL7756833 | 0.77 | TSHR (0.50) | CYP2A6ALDH1A1CA1CA2CA5A | |
| SCHEMBL4460794 | 0.77 | CYP2A6 (0.50) | CYP2A6ALDH1A1CA1CA2CA5A | |
| SCHEMBL31497684 | 0.77 | ESR1 (0.52) | CYP2A6ALDH1A1CA1CA2CA5A | |
| SCHEMBL9785061 | 0.77 | KIF11 (0.44) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5758 | 0.77 | TSHR (0.55) | CYP2A6ALDH1A1CA1CA2CA5A | |
| SCHEMBL5080121 | 0.77 | CYP2A6 (0.50) | CYP2A6ALDH1A1CA1CA2CA5A | |
| SCHEMBL3953416 | 0.77 | ESR1 (0.52) | CYP2A6ALDH1A1CA1CA2CA5A | |
| SCHEMBL15784485 | 0.77 | CYP2A6 (0.50) | CYP2A6ALDH1A1CA1CA2CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12492182-B2 | Hydroxytriazine compounds and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2025-12-09 | — | — | US | disclosed |
| US-20240076278-A1 | HYDROXYTRIAZINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2024-03-07 | — | — | US | disclosed |
| EP-4046991-A1 | HYDROXYTRIAZINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 2022-08-24 | — | — | EP | disclosed |
| CN-108137515-B | Hydroxy triazine compound and medical use thereof | 日本烟草产业株式会社 | 2021-07-06 | — | — | CN | disclosed |
| US-20210024486-A1 | HYDROXYTRIAZINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2021-01-28 | — | — | US | disclosed |
| EP-3339296-A1 | HYDROXYTRIAZINE COMPOUND AND MEDICAL USE THEREOF | Japan Tobacco, Inc. (JP) | 2018-06-27 | — | — | EP | disclosed |
| US-20170057943-A1 | HYDROXYTRIAZINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2017-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210024486-A1 | HYDROXYTRIAZINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | PTGS1, PTGIS, PTGES | CYP2A6 2164/4885ALDH1A1 618/4885CA1 617/4885 |
| US-20240076278-A1 | HYDROXYTRIAZINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | PTGS1, PTGIS, PTGES | CYP2A6 2164/4885ALDH1A1 618/4885CA1 617/4885 |
| US-12492182-B2 | Hydroxytriazine compounds and pharmaceutical use thereof | PTGS1, PTGIS, PTGES | CYP2A6 2164/4885ALDH1A1 618/4885CA1 617/4885 |
| US-20170057943-A1 | HYDROXYTRIAZINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | PTGS1, PTGIS, PTGES | CYP2A6 2164/4885ALDH1A1 618/4885CA1 617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.