SCHEMBL18548339

SCHEMBL18548339

CC1(C)COB(c2cccc(C3(C)CC3)c2)OC1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 1/20 0.36
MGLL Q99685 2/20 0.33
SNCA P37840 1/20 0.33
LPL P06858 1/20 0.31
LIPG Q9Y5X9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29808815 1.00 OPRD1 (0.36) OPRD1MGLLSNCALPLLIPG
SCHEMBL28578224 0.84 OPRD1 (0.35) OPRD1LPLLIPG
SCHEMBL16426133 0.84 SNCA (0.38) SNCALPLLIPG
SCHEMBL5892498 0.78 ALDH1A1 (0.36) SNCALPLLIPG
SCHEMBL5892480 0.78 ACHE (0.36) SNCALPLLIPG
SCHEMBL16674036 0.78 ACHE (0.38) MGLLSNCALPLLIPG
SCHEMBL3188699 0.77 ALDH1A1 (0.37) OPRD1SNCALPLLIPG
SCHEMBL5892466 0.77 MEN1 (0.38) SNCALPLLIPG
SCHEMBL1712145 0.77 CYP3A4 (0.37) SNCALPLLIPG
SCHEMBL2274567 0.75 LPL (0.42) SNCALPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12492182-B2 Hydroxytriazine compounds and pharmaceutical use thereof JAPAN TOBACCO INC. (JP) 2025-12-09 US disclosed
US-20240076278-A1 HYDROXYTRIAZINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF JAPAN TOBACCO INC. (JP) 2024-03-07 US disclosed
EP-4046991-A1 HYDROXYTRIAZINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF Japan Tobacco Inc. (JP) 2022-08-24 EP disclosed
US-20210024486-A1 HYDROXYTRIAZINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF JAPAN TOBACCO INC. (JP) 2021-01-28 US disclosed
US-20210024486-A1 HYDROXYTRIAZINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF JAPAN TOBACCO INC. (JP) 2021-01-28 US disclosed
EP-3339296-A1 HYDROXYTRIAZINE COMPOUND AND MEDICAL USE THEREOF Japan Tobacco, Inc. (JP) 2018-06-27 EP disclosed
US-20170057943-A1 HYDROXYTRIAZINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF JAPAN TOBACCO INC. (JP) 2017-03-02 US disclosed
US-20170057943-A1 HYDROXYTRIAZINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF JAPAN TOBACCO INC. (JP) 2017-03-02 US disclosed
US-20170057943-A1 HYDROXYTRIAZINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF JAPAN TOBACCO INC. (JP) 2017-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210024486-A1 HYDROXYTRIAZINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF PTGS1, PTGIS, PTGES OPRD1 2287/4885MGLL 2064/4885SNCA 2150/4885
US-20240076278-A1 HYDROXYTRIAZINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF PTGS1, PTGIS, PTGES OPRD1 2287/4885MGLL 2064/4885SNCA 2150/4885
US-12492182-B2 Hydroxytriazine compounds and pharmaceutical use thereof PTGS1, PTGIS, PTGES OPRD1 2287/4885MGLL 2064/4885SNCA 2150/4885
US-20170057943-A1 HYDROXYTRIAZINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF PTGS1, PTGIS, PTGES OPRD1 2287/4885MGLL 2064/4885SNCA 2150/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.