SCHEMBL18554

SCHEMBL18554

O=c1[nH]c(-c2ccnc(SCC(F)(F)F)n2)no1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
KMO O15229 1/20 0.35
DUSP10 Q9Y6W6 2/20 0.33
ALOX5 P09917 1/20 0.33
PLA2G2A P14555 2/20 0.32
RARB P10826 1/20 0.32
BPGM P07738 1/20 0.31
ADH5 P11766 1/20 0.31
MDM2 Q00987 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17877 0.76 KMO (0.39) ALDH1A1KMOALOX5RARBBPGM
SCHEMBL2336517 0.70 KMO (0.42) ALDH1A1KMOALOX5PLA2G2ARARB
SCHEMBL2340435 0.68 ALDH1A1 (0.42) ALDH1A1KMOPLA2G2A
SCHEMBL2338601 0.68 KMO (0.45) ALDH1A1KMOALOX5RARBADH5
SCHEMBL2335008 0.67 KMO (0.44) ALDH1A1KMOALOX5RARBADH5
SCHEMBL18186 0.66 ALDH1A1 (0.39) ALDH1A1ALOX5PLA2G2ARARBBPGM
SCHEMBL713240 0.66 ALOX5AP (0.37) ALDH1A1
SCHEMBL716823 0.66 L3MBTL1 (0.33) ALDH1A1DUSP10
SCHEMBL18781 0.65 ALDH1A1 (0.38) ALDH1A1KMOALOX5RARBADH5
SCHEMBL2332600 0.64 KMO (0.42) ALDH1A1KMOPLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012025460-A1 OXADIAZOLINONE DERIVATIVES AND USE THEREOF IN PEST CONTROL BAYER CROPSCIENCE AG (DE) 2012-03-01 WO disclosed