Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29654718 | 1.00 | TRPV4 (0.38) | TRPV4MAOAMAOBGRM4CYP11B2 | |
| SCHEMBL2732608 | 0.84 | GRM4 (0.33) | GRM4AR | |
| SCHEMBL52204 | 0.82 | TRPV4 (0.47) | TRPV4MAOAMAOBCYP11B2CYP11B1 | |
| SCHEMBL573864 | 0.78 | MAOB (0.53) | TRPV4MAOAMAOBCYP11B2CYP11B1 | |
| SCHEMBL18105636 | 0.78 | TRPV4 (0.36) | TRPV4MAOAMAOBCYP11B2CYP11B1 | |
| SCHEMBL24869692 | 0.77 | PKM (0.31) | ALDH1A1CYP1A2 | |
| SCHEMBL16959680 | 0.77 | PKM (0.31) | KDM4EALDH1A1CYP1A2 | |
| SCHEMBL2651278 | 0.77 | ABL1 (0.40) | CYP11B2CYP11B1 | |
| SCHEMBL1343188 | 0.76 | MAOB (0.44) | MAOAMAOBGRM4MEN1KMT2A | |
| SCHEMBL21116203 | 0.76 | USP8 (0.42) | TRPV4MAOAMAOBCYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 356 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476598-A | The two carbazole biphenyl derivatives for photoelectric device | 辛诺拉有限公司 | 2019-03-15 | — | — | CN | claimed |
| WO-2018001822-A1 | DICARBAZOLBIPHENYL DERIVATES FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2018-01-04 | — | — | WO | claimed |
| CN-1328996-A | Preparation of 2,4-dibromo-5-fluorobenzonitrile and 2,4-dibromo-5-fluorobenzoic acid by using ammonia oxidation process | UNIV WUHAN (CN) | 2002-01-02 | — | — | CN | claimed |
| EP-4105216-B1 | DIHYDRONAPHTHYRIDINONE COMPOUND, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | GENFLEET THERAPEUTICS SHANGHAI INC (CN) | 2026-05-20 | — | — | EP | disclosed |
| US-12492181-B2 | Gem-disubstituted piperidine melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2025-12-09 | — | — | US | disclosed |
| CN-119899179-A | AAK1 inhibitor and application thereof | 安润医药科技（苏州）有限公司 | 2025-04-29 | — | — | CN | disclosed |
| WO-2025072539-A1 | AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF | PLIANT THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |
| US-20250074909-A1 | AMINOTRIAZOLOPYRIDINES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2025-03-06 | — | — | US | disclosed |
| US-12157733-B2 | Aminotriazolopyridines as kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-12-03 | — | — | US | disclosed |
| CN-115677616-B | Macrocyclic sulfonamide compound, preparation method and medical application thereof | 中国药科大学 | 2024-10-18 | — | — | CN | disclosed |
| US-20240245682-A1 | ALPHA-V-BETA-8 INTEGRIN INHIBITORS AND USES THEREOF | PLIANT THERAPEUTICS, INC. | 2024-07-25 | — | — | US | disclosed |
| US-6319932-B1 | USEFUL FOR TREATING BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC. | 2001-11-20 | — | — | US | disclosed |
| US-6235759-B1 | BENIGN PROSTATIC HYPERPLASIA; HYPOTENSIVE AGENTS | MERCK & CO., INC. | 2001-05-22 | — | — | US | disclosed |
| US-6228870-B1 | BENIGN PROSTATIC HYPERPLASIA; REDUCTION OF HYPOTENSION SIDE EFFECT | MERCK & CO., INC. | 2001-05-08 | — | — | US | disclosed |
| EP-0411766-B1 | Substituted quinazolinones as angiotensin II antagonists | MERCK & CO INC (US) | 1994-01-19 | — | — | EP | disclosed |
| US-5240928-A | Hypotensive agents | MERCK & CO., INC. (US) | 1993-08-31 | — | — | US | disclosed |
| US-5238942-A | Hypotensive agents | MERCK & CO., INC. (US) | 1993-08-24 | — | — | US | disclosed |
| EP-0512870-A1 | Substituted quinazolinones bearing acidic functional groups as angiotensin II antagonists | MERCK & CO. INC. (US) | 1992-11-11 | — | — | EP | disclosed |
| EP-0411766-A1 | Substituted quinazolinones as angiotensin II antagonists | MERCK & CO. INC. (US) | 1991-02-06 | — | — | EP | disclosed |
| US-3966728-A | ANTIPEPTIC ULCER ACTIVITY | NIPPON SHINYAKU CO., LTD. (JA) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240245682-A1 | ALPHA-V-BETA-8 INTEGRIN INHIBITORS AND USES THEREOF | ITGB8, ITGAV, ITGA8 | TRPV4 3088/4885MAOA 4658/4885MAOB 4571/4885 |
| US-20250074909-A1 | AMINOTRIAZOLOPYRIDINES AS KINASE INHIBITORS | RIPK1, RIPK3, RIPK4 | TRPV4 1224/4885MAOA 4171/4885MAOB 3963/4885 |
| US-12492181-B2 | Gem-disubstituted piperidine melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof | MC1R, MC3R, MC2R | TRPV4 507/4885MAOA 1939/4885MAOB 1333/4885 |
| US-12157733-B2 | Aminotriazolopyridines as kinase inhibitors | RIPK1, RIPK3, RIPK4 | TRPV4 1224/4885MAOA 4171/4885MAOB 3963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.