Biphenyl

Biphenyl

SCHEMBL185563

Cc1ccc(NN)cc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.56
TDP1 Q9NUW8 3/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C9 P11712 1/20 0.56
IDO1 P14902 1/20 0.56
CYP2C19 P33261 1/20 0.56
PTGS2 P35354 1/20 0.56
HPGD P15428 2/20 0.54
MAPT P10636 7/20 0.53
ALDH1A1 P00352 4/20 0.53
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
AGTR1 P30556 1/20 0.50
HTT P42858 2/20 0.45
GAA P10253 2/20 0.44
KIF11 P52732 1/20 0.44
TSHR P16473 1/20 0.43
ALOX12 P18054 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL486107 0.85 TDP1 (0.68) LMNATDP1CYP1A2CYP3A4CYP2D6
SCHEMBL8096 0.85
Phenylhydrazine SCHEMBL27861422 0.83 TDP1 (0.74) LMNATDP1CYP1A2CYP3A4CYP2D6
Hydrochloric Acid SCHEMBL5664263 0.83 CYP3A4 (0.65) LMNATDP1CYP1A2CYP3A4CYP2D6
Biphenyl SCHEMBL27571445 0.83 TDP1 (0.82) LMNATDP1CYP1A2CYP3A4CYP2D6
Hydrochloric Acid SCHEMBL121455 0.83 MAPT (0.64) LMNATDP1CYP1A2CYP3A4CYP2D6
Hydrochloric Acid SCHEMBL23116894 0.80 MAPT (0.61) LMNATDP1CYP1A2CYP3A4CYP2D6
Dimethylamine SCHEMBL7258854 0.80 MAPT (0.61) LMNATDP1CYP1A2CYP3A4CYP2D6
Biphenyl SCHEMBL27808430 0.80 TDP1 (0.78) LMNATDP1CYP1A2CYP3A4CYP2D6
Biphenyl SCHEMBL28161913 0.80 ACHE (0.67) LMNATDP1CYP1A2HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 254 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140124763-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT MADE WITH THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2014-05-08 US claimed
US-11345686-B2 Aromatic amine derivative, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2022-05-31 US disclosed
US-20210384446-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2021-12-09 US disclosed
US-11133478-B2 Aromatic amine derivative and organic electroluminescent device using the same IDEMITSU KOSAN CO., LTD. (JP) 2021-09-28 US disclosed
EP-1722603-B2 ORGANIC ELECTROLUMINESCENT DEVICE IDEMITSU KOSAN CO (JP) 2021-02-17 EP disclosed
US-10454038-B2 Delayed-fluorescence material and organic electroluminescence element using same KYULUX, INC. (JP) 2019-10-22 US disclosed
US-20190237675-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2019-08-01 US disclosed
US-20190221753-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2019-07-18 US disclosed
US-20190177306-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2019-06-13 US disclosed
US-10312452-B2 Aromatic amine derivative and organic electroluminescence device utilizing the same IDEMITSU KOSAN CO., LTD. (JP) 2019-06-04 US disclosed
EP-1138744-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Idemitsu Kosan Co., Ltd. (JP) 2001-10-04 EP disclosed
EP-1138745-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN COMPANY LIMITED (JP) 2001-10-04 EP disclosed
EP-0786926-B1 Light-emitting material for organo-electroluminescence device and organo-electroluminescence devive for which the light-emitting material is adapted TOYO INK MFG CO (JP) 2001-08-22 EP disclosed
US-6251531-B1 LIGHT EMITTING LAYER BETWEEN ANODE AND CATHODE TOYO INK MANUFACTURING CO., LTD. (JP) 2001-06-26 US disclosed
EP-1061112-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN COMPANY LIMITED (JP) 2000-12-20 EP disclosed
EP-0965629-A1 Compound for organic electroluminescence device and organic electroluminescence device TOYO INK MFG. CO., LTD. (JP) 1999-12-22 EP disclosed
US-5811834-A Light-emitting material for organo-electroluminescence device and organo-electroluminescence device for which the light-emitting material is adapted TOYO INK MANUFACTURING CO., LTD. (JP) 1998-09-22 US disclosed
US-5759444-A FLAT LIGHT SOURCE OR DISPLAY; BRIGHTNESS, STABILITY TOYO INK MANUFACTURING CO., LTD. (JP) 1998-06-02 US disclosed
EP-0786926-A2 Light-emitting material for organo-electroluminescence device and organo-electroluminescence devive for which the light-emitting material is adapted TOYO INK MANUFACTURING CO., LTD. (JP) 1997-07-30 EP disclosed
EP-0765106-A2 Light-emitting material for organic electroluminescence device, and organic electroluminescence device for which the light-emitting material is adapted TOYO INK MANUFACTURING CO., LTD. (JP) 1997-03-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10312452-B2 Aromatic amine derivative and organic electroluminescence device utilizing the same TYR, OCIAD2, MAOA LMNA 2273/4885TDP1 990/4885CYP1A2 1349/4885
US-20210384446-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME DDT, TYR, DDC LMNA 2810/4885TDP1 809/4885CYP1A2 507/4885
US-11133478-B2 Aromatic amine derivative and organic electroluminescent device using the same DDT, TYR, DDC LMNA 2810/4885TDP1 809/4885CYP1A2 507/4885
US-20190177306-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT TYR, LEF1, EFNA1 LMNA 1720/4885TDP1 907/4885CYP1A2 156/4885
US-10454038-B2 Delayed-fluorescence material and organic electroluminescence element using same HNRNPF, RABL6, SRSF6 LMNA 2132/4885TDP1 2507/4885CYP1A2 4197/4885
US-11345686-B2 Aromatic amine derivative, and organic electroluminescent element TYR, LEF1, EFNA1 LMNA 1720/4885TDP1 907/4885CYP1A2 156/4885
US-20190221753-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME DDT, TYR, DDC LMNA 2810/4885TDP1 809/4885CYP1A2 507/4885
US-20190237675-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME TYR, NLRP1, NLRP3 LMNA 2737/4885TDP1 1007/4885CYP1A2 1172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.