SCHEMBL18556752

CC(=O)NCC(=O)NCC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)NCC(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O

nearest known ligand 0.52

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	CTSL	P07711	3/20	0.52

▸	CTSS	P25774	3/20	0.52

▸	CTSK	P43235	3/20	0.52

▸	GRPR	P30550	3/20	0.51

▸	OPRM1	P35372	2/20	0.51

▸	OPRD1	P41143	2/20	0.51

▸	CTSH	P09668	1/20	0.50

▸	ECE1	P42892	2/20	0.49

▸	KISS1R	Q969F8	2/20	0.48

▸	CCKBR	P32239	4/20	0.46

▸	NPBWR1	P48145	1/20	0.46

▸	MMP2	P08253	1/20	0.46

▸	MMP9	P14780	1/20	0.46

▸	MMP8	P22894	1/20	0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL18556704	0.95	OPRM1 (0.49)	CTSLCTSSCTSKGRPROPRM1
SCHEMBL18556712	0.92	KISS1R (0.55)	CTSLCTSSCTSKGRPROPRM1
SCHEMBL31016481	0.91	CTSL (0.56)	CTSLCTSSCTSKGRPROPRM1
SCHEMBL18556705	0.88	OPRD1 (0.63)	OPRM1OPRD1ECE1KISS1RCCKBR
SCHEMBL18556702	0.87	CCKBR (0.61)	GRPROPRD1KISS1RCCKBRNPBWR1
SCHEMBL18556706	0.86	KISS1R (0.50)	CTSLCTSSCTSKGRPROPRM1
SCHEMBL18556749	0.86	CCKBR (0.61)	GRPROPRD1KISS1RCCKBRNPBWR1
SCHEMBL31016496	0.84	OPRD1 (0.55)	CTSLCTSSCTSKGRPROPRM1
SCHEMBL18556700	0.82	CTSL (0.59)	CTSLCTSSCTSKGRPROPRM1
SCHEMBL31016483	0.82	CCKBR (0.57)	CTSLCTSSCTSKGRPROPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-9580466-B2	Melanocortin-1 receptor-specific linear peptides	PALATIN TECHNOLOGIES, INC. (US)	2017-02-28	—	—	US	disclosed