SCHEMBL1856347

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2259328	0.87	TAAR1 (0.57)	ALDH1A1MAPK1MAPTLMNASMN1; SMN2
	SCHEMBL430628	0.87	ALDH1A1 (0.51)	ALDH1A1MAPK1MAPTLMNASMN1; SMN2
	SCHEMBL3105068	0.86	SMN1; SMN2 (0.51)	ALDH1A1MAPK1MAPTLMNASMN1; SMN2
	SCHEMBL5051522	0.86	ALDH1A1 (0.50)	ALDH1A1MAPK1MAPTLMNASMN1; SMN2
	SCHEMBL30293228	0.83	ALDH1A1 (0.48)	ALDH1A1MAPK1MAPTLMNASMN1; SMN2
	SCHEMBL5050095	0.83	ALDH1A1 (0.48)	ALDH1A1MAPK1MAPTLMNASMN1; SMN2
	SCHEMBL8437108	0.83	ALDH1A1 (0.51)	ALDH1A1MAPK1MAPTLMNASMN1; SMN2
	SCHEMBL1289600	0.83	ALDH1A1 (0.49)	ALDH1A1MAPK1MAPTLMNASMN1; SMN2
	SCHEMBL21315650	0.82	SMN1; SMN2 (0.42)	ALDH1A1MAPK1MAPTLMNASMN1; SMN2
	SCHEMBL19783577	0.82	ALDH1A1 (0.51)	ALDH1A1MAPK1LMNASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.