Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIA | Q9BZP6 | 16/20 | 0.58 |
| ▸ | CHIT1 | Q13231 | 16/20 | 0.58 |
| ▸ | CHI3L1 | P36222 | 10/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.58 |
| ▸ | CHI3L2 | Q15782 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18589432 | 1.00 | CHIA (0.58) | CHIACHIT1CHI3L1KCNH2CHI3L2 | |
| SCHEMBL23169723 | 1.00 | CHIA (0.58) | CHIACHIT1CHI3L1KCNH2CHI3L2 | |
| SCHEMBL18609868 | 1.00 | CHIA (0.58) | CHIACHIT1CHI3L1KCNH2CHI3L2 | |
| SCHEMBL26439568 | 0.91 | KCNH2 (0.54) | CHIACHIT1CHI3L1KCNH2CHI3L2 | |
| SCHEMBL18608044 | 0.90 | CHIT1 (0.62) | CHIACHIT1CHI3L1KCNH2CHI3L2 | |
| SCHEMBL20747233 | 0.90 | CHIT1 (0.59) | CHIACHIT1CHI3L1KCNH2 | |
| SCHEMBL18607914 | 0.90 | CHIT1 (0.57) | CHIACHIT1CHI3L1KCNH2CHI3L2 | |
| SCHEMBL18589341 | 0.90 | CHIT1 (0.62) | CHIACHIT1CHI3L1KCNH2CHI3L2 | |
| SCHEMBL18577482 | 0.90 | CHIT1 (0.57) | CHIACHIT1CHI3L1KCNH2CHI3L2 | |
| SCHEMBL18607913 | 0.90 | CHIT1 (0.59) | CHIACHIT1CHI3L1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041726-B1 | PROCESS FOR THE PRODUCTION OF 5-(4-((2 S,5 S)-5-(4-CHLOROBENZYL)-2-METHYLMORPHOLINO)PIPERIDIN-1-YL)-1 H-1,2,4-TRIAZOL-3-AMINE | MOLECURE SA (PL) | 2025-09-17 | — | — | EP | claimed |
| US-11746107-B2 | Process for the production of 5-(4-((2S,5S)-5-(4-chlorobenzyl)-2-methyl-morpholino)piperidin-1-yl)-1H-1,2,4-triazol-3-amine | MOLECURE S.A. (PL) | 2023-09-05 | — | — | US | claimed |
| EP-4041726-A1 | PROCESS FOR THE PRODUCTION OF 5-(4-((2 S,5 S)-5-(4-CHLOROBENZYL)-2-METHYLMORPHOLINO)PIPERIDIN-1-YL)-1 H-1,2,4-TRIAZOL-3-AMINE | Molecure SA (PL) | 2022-08-17 | — | — | EP | claimed |
| US-20210147401-A1 | PROCESS FOR THE PRODUCTION OF 5-(4-((2S,5S)-5-(4-CHLOROBENZYL)-2-METHYL-MORPHOLINO)PIPERIDIN-1-YL)-1H-1,2,4-TRIAZOL-3-AMINE | Oncoarendi Therapeutics S.A. (PL) | 2021-05-20 | — | — | US | claimed |
| WO-2021059220-A1 | PROCESS FOR THE PRODUCTION OF 5-(4-((2 S,5 S)-5-(4-CHLOROBENZYL)-2-METHYLMORPHOLINO)PIPERIDIN-1-YL)-1 H-1,2,4-TRIAZOL-3-AMINE | Oncoarendi Therapeutics S.A. (PL) | 2021-04-01 | — | — | WO | claimed |
| EP-4041726-B1 | PROCESS FOR THE PRODUCTION OF 5-(4-((2 S,5 S)-5-(4-CHLOROBENZYL)-2-METHYLMORPHOLINO)PIPERIDIN-1-YL)-1 H-1,2,4-TRIAZOL-3-AMINE | MOLECURE SA (PL) | 2025-09-17 | — | — | EP | disclosed |
| US-12325701-B2 | YKL-40 inhibitors and their therapeutic | MOLECURE S.A. (PL) | 2025-06-10 | — | — | US | disclosed |
| US-12319677-B2 | Process for the production of 5-(4-((2S,5S)-5-(4-chlorobenzyl)-2-methyl-morpholino)piperidin-1-yl)-1H-1,2,4-triazol-3-amine | MOLECURE S.A. (PL) | 2025-06-03 | — | — | US | disclosed |
| US-20240025889-A1 | PROCESS FOR THE PRODUCTION OF 5-(4-((2S,5S)-5-(4-CHLOROBENZYL)-2-METHYL-MORPHOLINO)PIPERIDIN-1-YL)-1H-1,2,4-TRIAZOL-3-AMINE | Oncoarendi Therapeutics S.A. (PL) | 2024-01-25 | — | — | US | disclosed |
| US-20240025889-A1 | PROCESS FOR THE PRODUCTION OF 5-(4-((2S,5S)-5-(4-CHLOROBENZYL)-2-METHYL-MORPHOLINO)PIPERIDIN-1-YL)-1H-1,2,4-TRIAZOL-3-AMINE | Oncoarendi Therapeutics S.A. (PL) | 2024-01-25 | — | — | US | disclosed |
| US-20240025889-A1 | PROCESS FOR THE PRODUCTION OF 5-(4-((2S,5S)-5-(4-CHLOROBENZYL)-2-METHYL-MORPHOLINO)PIPERIDIN-1-YL)-1H-1,2,4-TRIAZOL-3-AMINE | Oncoarendi Therapeutics S.A. (PL) | 2024-01-25 | — | — | US | disclosed |
| US-20230278996-A1 | YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | MOLECURE S.A. (PL) | 2023-09-07 | — | — | US | disclosed |
| US-10208020-B2 | Substituted amino triazoles useful as human chitinase inhibitors | Oncoarendi Therapeutics S.A. (PL) | 2019-02-19 | — | — | US | disclosed |
| EP-3344616-B1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS HUMAN CHITINASE INHIBITORS | ONCOARENDI THERAPEUTICS SA (PL) | 2019-01-09 | — | — | EP | disclosed |
| US-20180258071-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS HUMAN CHITINASE INHIBITORS | GALAPAGOS NV (BE) | 2018-09-13 | — | — | US | disclosed |
| US-9944624-B2 | Substituted amino triazoles useful as human chitinase inhibitors | Oncoarendi Therapeutics S.A. (PL) | 2018-04-17 | — | — | US | disclosed |
| US-9944624-B2 | Substituted amino triazoles useful as human chitinase inhibitors | Oncoarendi Therapeutics S.A. (PL) | 2018-04-17 | — | — | US | disclosed |
| US-20170066743-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS HUMAN CHITINASE INHIBITORS | GALAPAGOS NV (BE) | 2017-03-09 | — | — | US | disclosed |
| US-20170066743-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS HUMAN CHITINASE INHIBITORS | GALAPAGOS NV (BE) | 2017-03-09 | — | — | US | disclosed |
| WO-2017037670-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS HUMAN CHITINASE INHIBITORS | OncoArendi Therapeutics Sp. z o.o. (PL) | 2017-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240025889-A1 | PROCESS FOR THE PRODUCTION OF 5-(4-((2S,5S)-5-(4-CHLOROBENZYL)-2-METHYL-MORPHOLINO)PIPERIDIN-1-YL)-1H-1,2,4-TRIAZOL-3-AMINE | NT5C, HTR5A, NT5C3B | CHIA 3506/4885CHIT1 1700/4885CHI3L1 4390/4885 |
| US-12319677-B2 | Process for the production of 5-(4-((2S,5S)-5-(4-chlorobenzyl)-2-methyl-morpholino)piperidin-1-yl)-1H-1,2,4-triazol-3-amine | NT5C, HTR5A, NT5C3B | CHIA 3506/4885CHIT1 1700/4885CHI3L1 4390/4885 |
| US-20230278996-A1 | YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | CHI3L1, CHI3L2, CHIA | CHIA 3/4885CHIT1 4/4885CHI3L1 1/4885 |
| US-20210147401-A1 | PROCESS FOR THE PRODUCTION OF 5-(4-((2S,5S)-5-(4-CHLOROBENZYL)-2-METHYL-MORPHOLINO)PIPERIDIN-1-YL)-1H-1,2,4-TRIAZOL-3-AMINE | NT5C, HTR5A, NT5C3B | CHIA 3506/4885CHIT1 1700/4885CHI3L1 4390/4885 |
| US-12325701-B2 | YKL-40 inhibitors and their therapeutic | CHI3L1, CHI3L2, CHIA | CHIA 3/4885CHIT1 5/4885CHI3L1 1/4885 |
| US-10208020-B2 | Substituted amino triazoles useful as human chitinase inhibitors | CHIA, CHIT1, AADAC | CHIA 1/4885CHIT1 2/4885CHI3L1 4/4885 |
| US-20170066743-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS HUMAN CHITINASE INHIBITORS | CHIA, CHIT1, AADAC | CHIA 1/4885CHIT1 2/4885CHI3L1 4/4885 |
| US-11746107-B2 | Process for the production of 5-(4-((2S,5S)-5-(4-chlorobenzyl)-2-methyl-morpholino)piperidin-1-yl)-1H-1,2,4-triazol-3-amine | NT5C, HTR5A, NT5C3B | CHIA 3506/4885CHIT1 1700/4885CHI3L1 4390/4885 |
| US-20180258071-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS HUMAN CHITINASE INHIBITORS | CHIA, CHIT1, AADAC | CHIA 1/4885CHIT1 2/4885CHI3L1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.