Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18579597 | 0.87 | ALDH1A1 (0.55) | ALDH1A1HTTHPGDRAB9APOLB | |
| SCHEMBL18579396 | 0.81 | ALDH1A1 (0.62) | ALDH1A1HTTHPGDRAB9APOLB | |
| SCHEMBL1369713 | 0.79 | ALDH1A1 (0.61) | ALDH1A1HTTHPGDRAB9APOLB | |
| SCHEMBL10478078 | 0.79 | RAB9A (0.60) | ALDH1A1HTTHPGDRAB9AKMT2A | |
| SCHEMBL12376683 | 0.79 | ALDH1A1 (0.69) | ALDH1A1HTTHPGDRAB9APOLB | |
| SCHEMBL13753433 | 0.76 | ALDH1A1 (0.60) | ALDH1A1HTTHPGDRAB9APOLB | |
| SCHEMBL13753321 | 0.75 | ALDH1A1 (0.61) | ALDH1A1HTTHPGDRAB9APOLB | |
| SCHEMBL963723 | 0.74 | HDAC1 (0.61) | ALDH1A1HTTHPGDRAB9APOLB | |
| SCHEMBL8760519 | 0.74 | HDAC1 (0.56) | ALDH1A1HTTHPGDRAB9APOLB | |
| SCHEMBL27543881 | 0.74 | ALDH1A1 (0.51) | ALDH1A1HTTHPGDRAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3107520-B1 | POLYMERIZABLE DENTAL MATERIAL | MUEHLBAUER TECH GMBH (DE) | 2019-10-30 | — | — | EP | disclosed |
| US-10058487-B2 | Polymerizable dental material | MUHLBAUER TECHNOLOGY GMBH (DE) | 2018-08-28 | — | — | US | disclosed |
| US-20170065496-A1 | POLYMERIZABLE DENTAL MATERIAL | MUHLBAUER TECHNOLOGY GMBH (DE) | 2017-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10058487-B2 | Polymerizable dental material | EHD1, ESD, HPD | ALDH1A1 335/4885HTT 246/4885HPGD 58/4885 |
| US-20170065496-A1 | POLYMERIZABLE DENTAL MATERIAL | EHD1, ESD, HPD | ALDH1A1 335/4885HTT 246/4885HPGD 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.