SCHEMBL18596991

SCHEMBL18596991

c1cc(-c2ccc3c4ccccc4c4ccc(-c5ccc6c7ccccc7c7cc(-c8cccc9c8sc8ccccc89)ccc7c6c5)cc4c3c2)cc(-c2cccc3c2sc2ccccc23)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.64
PRKDC P78527 5/20 0.46
PARP14 Q460N5 1/20 0.43
GPR3 P46089 1/20 0.39
TNKS O95271 1/20 0.39
TNKS2 Q9H2K2 1/20 0.39
F9 P00740 1/20 0.39
MAPT P10636 2/20 0.38
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PIK3CD O00329 2/20 0.37
PIK3CB P42338 2/20 0.37
BRD4 O60885 1/20 0.37
PIK3CA P42336 1/20 0.37
MTOR P42345 1/20 0.37
PIK3CG P48736 1/20 0.37
KCNH2 Q12809 1/20 0.37
BRDT Q58F21 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15179434 1.00 ALOX5 (0.64) ALOX5PRKDCPARP14GPR3TNKS
SCHEMBL126242 1.00 ALOX5 (0.64) ALOX5PRKDCPARP14GPR3TNKS
SCHEMBL12175700 1.00 ALOX5 (0.64) ALOX5PRKDCPARP14GPR3TNKS
SCHEMBL24609434 1.00 ALOX5 (0.64) ALOX5PRKDCPARP14GPR3TNKS
SCHEMBL806821 1.00 ALOX5 (0.64) ALOX5PRKDCPARP14GPR3TNKS
SCHEMBL24609435 1.00 ALOX5 (0.64) ALOX5PRKDCPARP14GPR3TNKS
SCHEMBL21249227 1.00 ALOX5 (0.64) ALOX5PRKDCPARP14GPR3TNKS
SCHEMBL21347677 1.00 ALOX5 (0.64) ALOX5PRKDCPARP14GPR3TNKS
SCHEMBL22360201 1.00 ALOX5 (0.64) ALOX5PRKDCPARP14GPR3TNKS
SCHEMBL29828423 1.00 ALOX5 (0.64) ALOX5PRKDCPARP14GPR3TNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11917902-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-02-27 US disclosed
US-10998508-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-05-04 US disclosed
US-10991896-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-04-27 US disclosed
US-10847729-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-11-24 US disclosed
US-10457699-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-10-29 US disclosed
US-20190326528-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-10-24 US disclosed
US-20190305231-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-10-03 US disclosed
US-20190071461-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-03-07 US disclosed
US-9725476-B2 Silylated metal complexes UNIVERSAL DISPLAY CORPORATION (US) 2017-08-08 US disclosed
US-9590194-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION 2017-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190305231-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES IRS1, L1CAM, TLL2 ALOX5 2401/4885PRKDC 4178/4885PARP14 3876/4885
US-10457699-B2 Organic electroluminescent materials and devices MLX, SSB, RPS4X ALOX5 1474/4885PRKDC 4766/4885PARP14 3559/4885
US-10991896-B2 Organic electroluminescent materials and devices L1CAM, AP1M1, EPCAM ALOX5 2089/4885PRKDC 4636/4885PARP14 3063/4885
US-20190071461-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, AP1M1, EPCAM ALOX5 2089/4885PRKDC 4636/4885PARP14 3063/4885
US-20190326528-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, NDUFV1, L1CAM ALOX5 2021/4885PRKDC 4284/4885PARP14 3824/4885
US-10847729-B2 Organic electroluminescent materials and devices OSBPL3, OR10J3, OSBP2 ALOX5 1772/4885PRKDC 4203/4885PARP14 3775/4885
US-10998508-B2 Organic electroluminescent materials and devices ORC3, OCIAD1, ICOSLG ALOX5 216/4885PRKDC 2325/4885PARP14 1843/4885
US-11917902-B2 Organic electroluminescent materials and devices SOD1, NDUFV1, L1CAM ALOX5 2021/4885PRKDC 4284/4885PARP14 3824/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.