SCHEMBL186063

SCHEMBL186063

CC(C)(CO)COC(=O)CCCCC(=O)O.OCCCC(O)(O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 3/20 0.42
FFAR1 O14842 1/20 0.42
FFAR4 Q5NUL3 1/20 0.42
CAMK2A Q9UQM7 1/20 0.36
TSHR P16473 4/20 0.35
PAM P19021 2/20 0.34
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
LMNA P02545 2/20 0.31
ALDH1A1 P00352 2/20 0.31
TBXAS1 P24557 2/20 0.31
P2RY10 O00398 1/20 0.31
GPR34 Q9UPC5 1/20 0.31
AKR1B1 P15121 1/20 0.31
NFKB1 P19838 1/20 0.31
PMP22 Q01453 1/20 0.31
DGKA P23743 1/20 0.30
PPARG P37231 3/20 0.30
PPARD Q03181 3/20 0.30
PPARA Q07869 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Butanediol SCHEMBL3703747 0.93 GPR84 (0.48) GPR84FFAR1FFAR4CAMK2ATSHR
1,6-Hexanediol SCHEMBL2487661 0.91 GPR84 (0.52) GPR84FFAR1FFAR4CAMK2ATSHR
SCHEMBL230981 0.88 TSHR (0.44) GPR84FFAR1FFAR4TSHRPAM
SCHEMBL8594577 0.86 PAM (0.44) GPR84FFAR1FFAR4TSHRPAM
SCHEMBL8522424 0.86 PAM (0.44) GPR84FFAR1FFAR4TSHRPAM
SCHEMBL7055063 0.86 DGKA (0.38) GPR84FFAR1FFAR4TSHRPAM
Butyl Alcohol SCHEMBL11037336 0.85 PAM (0.46) GPR84FFAR1FFAR4TSHRPAM
SCHEMBL274635 0.81 DGKA (0.42) TSHRPAMLMNAALDH1A1P2RY10
Dodecane SCHEMBL11247063 0.81 PAM (0.56) GPR84FFAR1FFAR4TSHRPAM
Acrylic Acid SCHEMBL8040754 0.79 TSHR (0.37) GPR84FFAR1FFAR4TSHRPAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2057203-B1 SILYLATED POLYURETHANE COMPOSITIONS AND ADHESIVES THEREFROM MOMENTIVE PERFORMANCE MAT INC (US) 2016-10-05 EP disclosed
US-8247079-B2 Laminate containing a silylated polyurethane adhesive composition MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-08-21 US disclosed
US-8247514-B2 partially silylated is especially useful for pressure sensitive adhesives where it imparts superior adhesive and cohesive performance; moisture-curable MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-08-21 US disclosed
EP-2104695-B1 ADHESIVE-FORMING COMPOSITION AND BLEND OF ADHESIVES OBTAINED THEREFROM MOMENTIVE PERFORMANCE MAT INC (US) 2012-01-04 EP disclosed
US-7976951-B2 Laminate containing an adhesive-forming composition MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2011-07-12 US disclosed
US-7829116-B2 Silylated polyurethanes; pressure sensitive adhesives; transdermal drug delivery MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-11-09 US disclosed
US-20090311459-A1 LAMINATE CONTAINING AN ADHESIVE-FORMING COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. 2009-12-17 US disclosed
EP-2104695-A2 ADHESIVE-FORMING COMPOSITION AND BLEND OF ADHESIVES OBTAINED THEREFROM Momentive Performance Materials Inc. (US) 2009-09-30 EP disclosed
US-20090233033-A1 Laminate containing a silylated polyurethane adhesive composition MOMENTIVE PERFORMANCE MATERIALS INC. 2009-09-17 US disclosed
EP-2057203-A2 SILYLATED POLYURETHANE COMPOSITIONS AND ADHESIVES THEREFROM Momentive Performance Materials Inc. (US) 2009-05-13 EP disclosed
WO-2008060506-A2 ADHESIVE-FORMING COMPOSITION AND BLEND OF ADHESIVES OBTAINED THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-05-22 WO disclosed
US-20080114098-A1 Adhesive-forming composition and blend of adhesives obtained therefrom GENERAL ELECTRIC COMPANY (US) 2008-05-15 US disclosed
US-20080058492-A1 Silylated polyurethane compositions and adhesives therefrom GENERAL ELECTRIC COMPANY (US) 2008-03-06 US disclosed
WO-2008027496-A2 SILYLATED POLYURETHANE COMPOSITIONS AND ADHESIVES THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-03-06 WO disclosed