1,4-Butanediol

1,4-Butanediol

SCHEMBL3703747

CC(C)(CO)COC(=O)CCCCC(=O)O.OCCCCO

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 6/20 0.48
FFAR1 O14842 2/20 0.48
FFAR4 Q5NUL3 2/20 0.48
CAMK2A Q9UQM7 1/20 0.42
TSHR P16473 6/20 0.40
PAM P19021 2/20 0.39
LMNA P02545 2/20 0.37
NFKB1 P19838 1/20 0.35
PMP22 Q01453 1/20 0.35
AKR1B1 P15121 1/20 0.35
ALDH1A1 P00352 3/20 0.35
PPARG P37231 6/20 0.34
PPARD Q03181 6/20 0.34
PPARA Q07869 6/20 0.34
HDAC11 Q96DB2 5/20 0.34
TLR2 O60603 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
FABP4 P15090 2/20 0.34
PTPN1 P18031 2/20 0.34
SLC22A6 Q4U2R8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,6-Hexanediol SCHEMBL2487661 0.98 GPR84 (0.52) GPR84FFAR1FFAR4CAMK2ATSHR
SCHEMBL230981 0.95 TSHR (0.44) GPR84FFAR1FFAR4TSHRPAM
SCHEMBL8594577 0.93 PAM (0.44) GPR84FFAR1FFAR4TSHRPAM
SCHEMBL8522424 0.93 PAM (0.44) GPR84FFAR1FFAR4TSHRPAM
SCHEMBL7055063 0.93 DGKA (0.38) GPR84FFAR1FFAR4TSHRPAM
SCHEMBL186063 0.93 GPR84 (0.42) GPR84FFAR1FFAR4CAMK2ATSHR
Butyl Alcohol SCHEMBL11037336 0.92 PAM (0.46) GPR84FFAR1FFAR4TSHRPAM
SCHEMBL274635 0.88 DGKA (0.42) TSHRPAMLMNAALDH1A1TDP1
Dodecane SCHEMBL11247063 0.87 PAM (0.56) GPR84FFAR1FFAR4TSHRPAM
Acrylic Acid SCHEMBL8040754 0.86 TSHR (0.37) GPR84FFAR1FFAR4TSHRPAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113072679-A Radiation-curable benzophenone end-capped polyurethane resin and application thereof 深圳力合博汇光敏材料有限公司 2021-07-06 CN disclosed
EP-2057203-B1 SILYLATED POLYURETHANE COMPOSITIONS AND ADHESIVES THEREFROM MOMENTIVE PERFORMANCE MAT INC (US) 2016-10-05 EP disclosed
EP-2203492-B1 SOFT, ELASTIC, PLASTICIZER-FREE THERMOPLASTIC POLYURETHANE AND PROCESS TO SYNTHESIZE THE SAME LUBRIZOL ADVANCED MAT INC (US) 2015-12-23 EP disclosed
EP-1971656-B1 SILYLATED POLYURENTHANE-POLYUREA PROTECTIVE COATING COMPOSITIONS MOMENTIVE PERFORMANCE MAT INC (US) 2013-07-24 EP disclosed
US-8247514-B2 partially silylated is especially useful for pressure sensitive adhesives where it imparts superior adhesive and cohesive performance; moisture-curable MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-08-21 US disclosed
US-8247079-B2 Laminate containing a silylated polyurethane adhesive composition MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-08-21 US disclosed
US-8183330-B2 Soft, elastic, plasticizer-free thermoplastic polyurethane and process to synthesize the same LUBRIZOL ADVANCED MATERIALS, INC. (US) 2012-05-22 US disclosed
EP-2203492-A1 SOFT, ELASTIC, PLASTICIZER-FREE THERMOPLASTIC POLYURETHANE AND PROCESS TO SYNTHESIZE THE SAME Lubrizol Advanced Materials, Inc. (US) 2010-07-07 EP disclosed
CN-101600747-A The polyurethane composition of silanization and tackiness agent therefrom MOMENTIVE PERFORMANCE MAT INC (US) 2009-12-09 CN disclosed
US-20090233033-A1 Laminate containing a silylated polyurethane adhesive composition MOMENTIVE PERFORMANCE MATERIALS INC. 2009-09-17 US disclosed
US-20080058492-A1 Silylated polyurethane compositions and adhesives therefrom GENERAL ELECTRIC COMPANY (US) 2008-03-06 US disclosed
WO-2008027496-A2 SILYLATED POLYURETHANE COMPOSITIONS AND ADHESIVES THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-03-06 WO disclosed
WO-2007067531-A1 SILYLATED POLYURENTHANE-POLYUREA PROTECTIVE COATING COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2007-06-14 WO disclosed
US-20070129527-A1 Silylated polyurethane-polyurea protective coating compositions MOMENTIVE PERFORMANCE MATERIALS INC. 2007-06-07 US disclosed
US-5618904-A REACTION PRODUCT OF POLYESTER POLYOL OR MIXTURE OF POLYESTER POLYOL AND POLYETHER POLYOL, POLYISOCYANATE, HYDROQUINONE BIS/2-HYDROXYETHYL/ ETHER ESSEX SPECIALTY PRODUCTS INC. (US) 1997-04-08 US disclosed
US-5506328-A LOW VOLATILITY OLIN CORPORATION (US) 1996-04-09 US disclosed
US-5391614-A Low-viscosity prepolymer of a polyisocyanate and a monoahl, polyol, imine or oxazolidine and a hydroxy-containing amine as catalyst; polyureas; fast-drying OLIN CORPORATION (US) 1995-02-21 US disclosed
WO-1994027743-A1 MOISTURE CURABLE, ONE-COMPONENT COATING COMPOSITIONS OLIN CORPORATION (US) 1994-12-08 WO disclosed
WO-1994027746-A1 MOISTURE CURABLE, TWO-COMPONENT COATING COMPOSITIONS OLIN CORPORATION (US) 1994-12-08 WO disclosed
US-5360642-A Low volatility organic OLIN CORPORATION (US) 1994-11-01 US disclosed