Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 13/20 | 0.41 |
| ▸ | RARB | P10826 | 7/20 | 0.39 |
| ▸ | RARG | P13631 | 7/20 | 0.38 |
| ▸ | RARA | P10276 | 6/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 5/20 | 0.35 |
| ▸ | RXRG | P48443 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15347776 | 0.79 | RXRA (0.50) | RXRARARBRARGRARACYP1A2 | |
| SCHEMBL9867919 | 0.74 | RXRA (0.44) | RXRARARBRARGRARACYP1A2 | |
| SCHEMBL18327675 | 0.71 | RXRA (0.45) | RXRARARBRARGRARACYP1A2 | |
| SCHEMBL6224470 | 0.71 | RXRA (0.46) | RXRARARBRARGRARACYP1A2 | |
| SCHEMBL19831160 | 0.70 | RXRA (0.37) | RXRARARBRARGRARACYP1A2 | |
| SCHEMBL7806009 | 0.69 | RXRA (0.44) | RXRARARBRARGRARACYP1A2 | |
| SCHEMBL5846259 | 0.69 | RXRA (0.46) | RXRARARBRARGRARACYP1A2 | |
| SCHEMBL19101607 | 0.69 | CYP1A2 (0.42) | RXRARARBRARGRARACYP1A2 | |
| SCHEMBL11599145 | 0.68 | RXRA (0.42) | RXRARARBRARGRARACYP1A2 | |
| SCHEMBL23633278 | 0.67 | ALDH1A1 (0.54) | RXRARARBRARGRARACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170066711-A1 | METHOD FOR PRODUCING AN ARENE WITH AN AROMATIC C-N BOND ORTHO TO AN AROMATIC C-O BOND | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2017-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170066711-A1 | METHOD FOR PRODUCING AN ARENE WITH AN AROMATIC C-N BOND ORTHO TO AN AROMATIC C-O BOND | AOX1, NOX4, NOXO1 | RXRA 1310/4885RARB 1021/4885RARG 1578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.