Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | RARA | P10276 | 1/20 | 0.30 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20341801 | 0.84 | — | — | |
| SCHEMBL23810290 | 0.84 | CTSL (0.33) | — | |
| SCHEMBL20341745 | 0.77 | SMN1; SMN2 (0.42) | MAPTSMN1; SMN2TSHRHTTMEN1 | |
| SCHEMBL18615936 | 0.75 | MAOA (0.33) | SMN1; SMN2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL20341862 | 0.75 | BMPR1B (0.36) | MAPTSMN1; SMN2MEN1NPC1RAB9A | |
| SCHEMBL23810222 | 0.74 | NPC1 (0.48) | MAPTSMN1; SMN2MEN1NPC1RAB9A | |
| SCHEMBL20341831 | 0.74 | MAPT (0.32) | MAPTMEN1RAB9AKMT2A | |
| SCHEMBL18615951 | 0.73 | BMPR1B (0.35) | MAPTSMN1; SMN2MEN1NPC1RAB9A | |
| SCHEMBL23810225 | 0.70 | CA1 (0.37) | RAB9A | |
| SCHEMBL23810300 | 0.70 | KDM4E (0.35) | SMN1; SMN2TSHRMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017036357-A1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | 广东东阳光药业有限公司 | 2017-03-09 | — | — | WO | disclosed |