Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMPR1B | O00238 | 1/20 | 0.35 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20341862 | 0.91 | BMPR1B (0.36) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL18615936 | 0.83 | MAOA (0.33) | ALDH1A1LMNATHRBTAS1R3TAS1R1 | |
| SCHEMBL18615950 | 0.81 | CTSK (0.41) | CTSK | |
| SCHEMBL23810222 | 0.80 | NPC1 (0.48) | ALDH1A1LMNAMEN1KMT2ARAB9A | |
| SCHEMBL20341831 | 0.80 | MAPT (0.32) | ALDH1A1HDAC6MEN1KMT2ARAB9A | |
| SCHEMBL23810304 | 0.75 | RAB9A (0.39) | ALDH1A1LMNAMEN1KMT2ARAB9A | |
| SCHEMBL18615964 | 0.75 | CTSL (0.44) | CTSK | |
| SCHEMBL18616494 | 0.74 | CTSL (0.43) | HDAC6ROCK2 | |
| SCHEMBL20341790 | 0.74 | NAMPT (0.42) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL20341745 | 0.74 | SMN1; SMN2 (0.42) | ALDH1A1LMNATHRBHDAC6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017036357-A1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | 广东东阳光药业有限公司 | 2017-03-09 | — | — | WO | disclosed |