Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.37 |
| ▸ | CA2 | P00918 | 5/20 | 0.37 |
| ▸ | CA9 | Q16790 | 5/20 | 0.37 |
| ▸ | F11 | P03951 | 3/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18615954 | 0.82 | CTSL (0.38) | CA1CA2CA9 | |
| SCHEMBL20612434 | 0.80 | ALDH1A1 (0.44) | CA1CA2CA9ALDH1A1RAB9A | |
| SCHEMBL18615936 | 0.76 | MAOA (0.33) | ALDH1A1RAB9ACHRNA7HTR3ALMNA | |
| SCHEMBL20562375 | 0.76 | CSF1R (0.41) | CA1CA2CA9F11LIPG | |
| SCHEMBL18615903 | 0.74 | CTSL (0.46) | CA1CA2CA9 | |
| SCHEMBL18615951 | 0.73 | BMPR1B (0.35) | ALDH1A1RAB9ALMNATHRB | |
| SCHEMBL28650123 | 0.73 | CSF1R (0.39) | CA1CA2CA9F11F2 | |
| SCHEMBL23810222 | 0.73 | NPC1 (0.48) | ALDH1A1RAB9ALMNA | |
| SCHEMBL24943919 | 0.71 | TAS1R3 (0.49) | ALDH1A1RAB9ALMNATHRB | |
| SCHEMBL18615914 | 0.70 | MAPT (0.31) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342765-B1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2021-09-15 | — | — | EP | disclosed |