Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19155894 | 0.79 | PDE3B (0.43) | PDE3BPDE3APOLBRAD52SMN1; SMN2 | |
| SCHEMBL10078327 | 0.78 | CYP2A6 (0.47) | PDE3BPDE3AALDH1A1CYP1A2POLB | |
| SCHEMBL7510548 | 0.74 | NOS3 (0.44) | ALDH1A1CYP1A2POLBGAAKDM4E | |
| SCHEMBL30505983 | 0.74 | LMNA (0.43) | ALDH1A1CYP1A2POLBSMN1; SMN2KDM4E | |
| SCHEMBL34466619 | 0.74 | MAPT (0.52) | PDE3BPDE3ASMN1; SMN2GRM4KDM4E | |
| SCHEMBL12983661 | 0.74 | MAPT (0.52) | PDE3BPDE3ASMN1; SMN2GRM4KDM4E | |
| SCHEMBL24656745 | 0.72 | ALDH1A1 (0.37) | ALDH1A1CYP1A2POLBALOX15GRM4 | |
| SCHEMBL15268029 | 0.72 | CYP1A2 (0.41) | ALDH1A1CYP1A2SMN1; SMN2ALOX15KDM4E | |
| SCHEMBL25952898 | 0.72 | PDE3B (0.44) | PDE3BPDE3AGRM4 | |
| SCHEMBL8571925 | 0.71 | ALDH1A1 (0.53) | ALDH1A1CYP1A2POLBGAAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170073344-A1 | Compound as WNT Signaling Inhibitor, Composition, and Use Thereof | CUREGENIX, INC. (CN) | 2017-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170073344-A1 | Compound as WNT Signaling Inhibitor, Composition, and Use Thereof | WNT1, WNT3A, SFRP1 | PDE3B 2167/4885PDE3A 3229/4885PDE10A 2331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.