SCHEMBL1870282

SCHEMBL1870282

N#Cc1ccc(-c2nc(-c3ccccc3)c(-c3ccccc3)n2C2(c3ccc(C#N)cc3C#N)N=C(c3ccccc3)C(c3ccccc3)=N2)c(C#N)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 6/20 0.38
AKT2 P31751 6/20 0.38
ALDH1A1 P00352 3/20 0.36
LMNA P02545 1/20 0.36
THRB P10828 1/20 0.36
KDM4E B2RXH2 1/20 0.33
HTT P42858 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
HPGD P15428 1/20 0.32
GABRA1 P14867 1/20 0.32
GABRG2 P18507 1/20 0.32
GABRB3 P28472 1/20 0.32
GABRA5 P31644 1/20 0.32
GABRA3 P34903 1/20 0.32
GABRA2 P47869 1/20 0.32
ADORA2A P29274 3/20 0.32
ADORA1 P30542 2/20 0.32
CYP19A1 P11511 3/20 0.31
BAZ2B Q9UIF8 1/20 0.31
BAZ2A Q9UIF9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1864620 0.84 TNK2 (0.37) AKT1AKT2ALDH1A1LMNATHRB
SCHEMBL1866679 0.78 ALDH1A1 (0.35) AKT1AKT2ALDH1A1LMNATHRB
SCHEMBL1614534 0.76 ALDH1A1 (0.37) AKT1AKT2ALDH1A1LMNAKDM4E
SCHEMBL1869867 0.76 BCHE (0.32) AKT1AKT2
SCHEMBL17133349 0.75 BCHE (0.36) AKT1AKT2ALDH1A1LMNAKDM4E
SCHEMBL476565 0.75 HSD11B1 (0.42) ALDH1A1LMNAKDM4EHPGD
SCHEMBL29389827 0.75 HSD11B1 (0.42) ALDH1A1LMNAKDM4EHPGD
SCHEMBL1865434 0.73 FABP4 (0.35) AKT1AKT2ALDH1A1LMNAKDM4E
SCHEMBL476661 0.73 MGAM (0.34) AKT1AKT2
SCHEMBL29392749 0.73 MGAM (0.34) AKT1AKT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1999514-B1 PHOTOSENSITIVE RESIST COMPOSITION FOR COLOR FILTERS FOR USE IN ELECTRONIC PAPER DISPLAY DEVICES CIBA HOLDING INC (CH) 2018-10-03 EP disclosed
US-8927182-B2 Photosensitive resist composition for color filters for use in electronic paper display devices BASF SE (DE) 2015-01-06 US disclosed
US-7935776-B2 having a carboxy group in its main chain and a acryloyl group in its side chain; Color filters AGI CORPORATION (TW) 2011-05-03 US disclosed
US-7785501-B2 Black resin composition for display device, and member for display device DAI NIPPON PRINTING CO., LTD. (JP) 2010-08-31 US disclosed
US-20100164911-A1 PHOTOSENSITIVE RESIST COMPOSITION FOR COLOR FILTERS FOR USE IN ELECTRONIC PAPER DISPLAY DEVICES CIBA CORPORATION 2010-07-01 US disclosed
US-20080318018-A1 Black Resin Composition for Display Device, and Member for Display Device DAI NIPPON PRINTING CO., LTD. (JP) 2008-12-25 US disclosed
EP-1999514-A1 PHOTOSENSITIVE RESIST COMPOSITION FOR COLOR FILTERS FOR USE IN ELECTRONIC PAPER DISPLAY DEVICES Ciba Holding Inc. (CH) 2008-12-10 EP disclosed
US-20080234403-A1 Radiation curable and developable polyurethane and radiation curable and developable photo resist composition containing the same AGI CORPORATION (TW) 2008-09-25 US disclosed
WO-2007113107-A1 PHOTOSENSITIVE RESIST COMPOSITION FOR COLOR FILTERS FOR USE IN ELECTRONIC PAPER DISPLAY DEVICES CIBA HOLDING INC. (CH) 2007-10-11 WO disclosed
EP-1048700-B1 Ink jet color filter resin composition, color filter production process SEIKO EPSON CORP (JP) 2006-11-02 EP disclosed
US-6120973-A PHOTOSENSITIVE COMPOSITION AND COLORS WITH POLYMERS JSR CORPORATION (JP) 2000-09-19 US disclosed
EP-1033625-A1 Radiation sensitive composition JSR Corporation (JP) 2000-09-06 EP disclosed
EP-1033626-A1 Radiation sensitive composition JSR Corporation (JP) 2000-09-06 EP disclosed
US-6087050-A Radiation sensitive composition and color filter JSR CORPORATION (JP) 2000-07-11 US disclosed
US-6013415-A Radiation sensitive composition JSR CORPORATION (JP) 2000-01-11 US disclosed
EP-0902327-A2 Radiation sensitive composition JSR Corporation (JP) 1999-03-17 EP disclosed
EP-0893737-A2 Radiation sensitive composition JSR Corporation (JP) 1999-01-27 EP disclosed
EP-0881541-A1 Radiation sensitive composition and color filter JSR Corporation (JP) 1998-12-02 EP disclosed
EP-0875788-A1 Radiation sensitive composition for color filters JSR Corporation (JP) 1998-11-04 EP disclosed
EP-0866367-A2 Radiation sensitive composition JSR Corporation (JP) 1998-09-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100164911-A1 PHOTOSENSITIVE RESIST COMPOSITION FOR COLOR FILTERS FOR USE IN ELECTRONIC PAPER DISPLAY DEVICES EYA2, PTPN4, PTPN5 AKT1 1547/4885AKT2 1443/4885ALDH1A1 3019/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.