Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 11/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18654645 | 0.88 | SCN9A (0.35) | NTRK1SCN10ASCN9ASCN5ASCN2A | |
| SCHEMBL18654742 | 0.88 | RIPK1 (0.40) | RIPK1NTRK1SCN10ASCN9ASCN5A | |
| SCHEMBL18654323 | 0.87 | NTRK1 (0.35) | NTRK1CSNK1DCSNK1E | |
| SCHEMBL18654626 | 0.86 | CSNK1D (0.37) | CSNK1DCSNK1E | |
| SCHEMBL18654740 | 0.86 | RIPK1 (0.40) | RIPK1NTRK1FYN | |
| SCHEMBL18654723 | 0.84 | EPHB3 (0.40) | CSNK1DCSNK1E | |
| SCHEMBL18654658 | 0.84 | EPHB3 (0.35) | CSNK1DCSNK1E | |
| SCHEMBL18654629 | 0.84 | MAPT (0.39) | RIPK1NTRK1SCN9A | |
| SCHEMBL18655294 | 0.83 | FYN (0.40) | RIPK1SCN10ADYRK1AFYN | |
| SCHEMBL14896757 | 0.83 | NAMPT (0.45) | RIPK1SCN10ASCN9ASCN5ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2768509-B1 | SUBSTITUTED BICYCLIC AZA-HETEROCYCLES AND ANALOGUES AS SIRTUIN MODULATORS | GLAXOSMITHKLINE LLC (US) | 2017-03-22 | — | — | EP | disclosed |