Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Methyltestosterone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR known ✓ | P10275 | 3/20 | 0.72 |
| ▸ | SHBG | P04278 | 9/20 | 1.00 |
| ▸ | NR3C1 | P04150 | 5/20 | 1.00 |
| ▸ | PGR | P06401 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | ADRA1A | P35348 | 1/20 | 1.00 |
| ▸ | HTR2B | P41595 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 8/20 | 0.74 |
| ▸ | SERPINA6 | P08185 | 7/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.74 |
| ▸ | BLM | P54132 | 4/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.74 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.74 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 5/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyltestosterone SCHEMBL18657 | 1.00 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL6472960 | 1.00 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL4442874 | 1.00 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL5021655 | 1.00 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL18891626 | 1.00 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL13575766 | 1.00 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL13965283 | 1.00 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL13768123 | 1.00 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL6152059 | 1.00 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL4575985 | 1.00 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120058450-A | C (sp) in benzene ring2) Method for deuteration of the H bond | 云南大学 | 2025-05-30 | — | — | CN | claimed |
| CN-110198949-B | Process for the preparation of 9 beta, 10 alpha-progesterone (retroprogesterone) | 工业化学有限公司 | 2022-05-10 | — | — | CN | claimed |
| CN-120058450-A | C (sp) in benzene ring2) Method for deuteration of the H bond | 云南大学 | 2025-05-30 | — | — | CN | disclosed |
| CN-116789726-A | Steroid compound, preparation method and application thereof | 珂阑(上海)医药科技有限公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-116514892-A | Steroid compound, preparation method and application thereof | 珂阑(上海)医药科技有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-116514893-A | Steroid compound, preparation method and application thereof | 珂阑(上海)医药科技有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-107735101-B | Antibiotic sensitivity restoring agent and photosensitizer | 新墨西哥州科技研究基金会 | 2022-11-04 | — | — | CN | disclosed |
| CN-115160397-A | Androstane derivative and preparation method and application thereof | 天津红日药业股份有限公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-112110880-B | Androstane derivative and preparation method and application thereof | 天津红日药业股份有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-114466855-A | Androstane derivatives with pure or significantly pure stimulant activity as SERCA2a for the treatment of heart failure | 风树疗法公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-110198949-B | Process for the preparation of 9 beta, 10 alpha-progesterone (retroprogesterone) | 工业化学有限公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-114106077-A | Abiraterone derivative and preparation and application thereof | 广东中科药物研究有限公司 | 2022-03-01 | — | — | CN | disclosed |