Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 7/20 | 0.45 |
| ▸ | CA12 | O43570 | 5/20 | 0.45 |
| ▸ | CA1 | P00915 | 5/20 | 0.45 |
| ▸ | CA2 | P00918 | 5/20 | 0.45 |
| ▸ | CA9 | Q16790 | 5/20 | 0.45 |
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | MMP8 | P22894 | 2/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Incadronic Acid SCHEMBL223885 | 0.80 | ANPEP (0.48) | ANPEPERAP2MMP2CA12CA1 | |
| (Cyclohexylamino)Methylenediphosphonic Acid SCHEMBL8370913 | 0.80 | ANPEP (0.48) | ANPEPERAP2MMP2CA12CA1 | |
| (Cyclooctylamino)Methylenediphosphonic Acid SCHEMBL9777403 | 0.80 | ANPEP (0.48) | ANPEPERAP2MMP2CA12CA1 | |
| (Cyclopentylamino)Methylenediphosphonic Acid SCHEMBL9626232 | 0.77 | ANPEP (0.46) | ANPEPERAP2MMP2CA12CA1 | |
| Incadronic Acid SCHEMBL2898450 | 0.77 | ANPEP (0.46) | ANPEPERAP2MMP2CA12CA1 | |
| SCHEMBL15397148 | 0.77 | MMP2 (0.46) | ANPEPERAP2MMP2CA12CA1 | |
| (Cyclobutylamino)Methylenediphosphonic Acid SCHEMBL9626988 | 0.73 | MMP2 (0.45) | ANPEPERAP2MMP2CA12CA1 | |
| Incadronic Acid SCHEMBL2898447 | 0.71 | ANPEP (0.41) | ANPEPERAP2MMP2CA12CA1 | |
| Incadronic Acid SCHEMBL29355743 | 0.71 | MMP2 (0.42) | ANPEPERAP2MMP2CA12CA1 | |
| SCHEMBL27992126 | 0.71 | KDM4E (0.48) | KDM4EEPHX1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170079995-A1 | DOSAGE FORMS FOR ORAL ADMINISTRATION OF ZOLEDRONIC ACID OR RELATED COMPOUNDS FOR TREATING DISEASE | ANTECIP BIOVENTURES II LLC | 2017-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170079995-A1 | DOSAGE FORMS FOR ORAL ADMINISTRATION OF ZOLEDRONIC ACID OR RELATED COMPOUNDS FOR TREATING DISEASE | SLC10A1, SOST, SLC10A6 | ANPEP 3711/4885ERAP2 4458/4885MMP2 2542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.