SCHEMBL18674264

SCHEMBL18674264

C=C(C)C(=O)OC1(CC)CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CTSK P43235 1/20 0.38
HPGD P15428 1/20 0.36
EPHX2 P34913 1/20 0.36
RECQL P46063 1/20 0.35
EPHX1 P07099 1/20 0.35
DDB1 Q16531 1/20 0.34
CRBN Q96SW2 1/20 0.34
NR1H2 P55055 1/20 0.34
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
ALOX15 P16050 1/20 0.34
TSHR P16473 1/20 0.34
ATM Q13315 1/20 0.34
TACR1 P25103 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18674259 0.82 USP2 (0.44) USP2SMN1; SMN2HPGDEPHX2RECQL
SCHEMBL2943334 0.80 USP2 (0.47) USP2SMN1; SMN2CTSKHPGDEPHX2
SCHEMBL18674256 0.80 USP2 (0.42) USP2SMN1; SMN2CTSKHPGDEPHX2
SCHEMBL20414907 0.79 CTSK (0.50) USP2SMN1; SMN2CTSKHPGDEPHX2
SCHEMBL18674243 0.78 USP2 (0.41) USP2SMN1; SMN2HPGDEPHX2RECQL
SCHEMBL673334 0.77 ALDH1A1 (0.39) ALDH1A1TSHR
SCHEMBL18674244 0.75 EPHX1 (0.43) USP2SMN1; SMN2HPGDEPHX2RECQL
SCHEMBL21134747 0.75 USP2 (0.38) USP2SMN1; SMN2HPGDEPHX2DDB1
SCHEMBL7750228 0.75 USP2 (0.49) USP2SMN1; SMN2HPGDEPHX2RECQL
SCHEMBL18314373 0.75 USP2 (0.43) USP2SMN1; SMN2HPGDEPHX2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113527571-B Polymer, primer composition comprising the same, and patterning method 罗门哈斯电子材料韩国有限公司 2023-08-04 CN disclosed
US-11567409-B2 Polymers, underlayer coating compositions comprising the same, and patterning methods ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2023-01-31 US disclosed
CN-113527571-A Polymer, primer composition comprising same, and patterning method 罗门哈斯电子材料韩国有限公司 2021-10-22 CN disclosed
US-20210324122-A1 POLYMERS, UNDERLAYER COATING COMPOSITIONS COMPRISING THE SAME, AND PATTERNING METHODS DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-10-21 US disclosed
US-11016388-B2 Overcoat compositions and methods for photolithography ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2021-05-25 US disclosed
US-10564542-B2 Photoresist compositions and methods DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2020-02-18 US disclosed
US-20170090287-A1 OVERCOAT COMPOSITIONS AND METHODS FOR PHOTOLITHOGRAPHY DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-03-30 US disclosed
US-20170090283-A1 PHOTORESIST COMPOSITIONS AND METHODS DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-03-30 US disclosed
US-20170090283-A1 PHOTORESIST COMPOSITIONS AND METHODS DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-03-30 US disclosed
US-20170090287-A1 OVERCOAT COMPOSITIONS AND METHODS FOR PHOTOLITHOGRAPHY DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11016388-B2 Overcoat compositions and methods for photolithography OGT, COLGALT1, PARG USP2 717/4885SMN1; SMN2 4742/4885CTSK 1573/4885
US-10564542-B2 Photoresist compositions and methods PARG, PNN, PARN USP2 2213/4885SMN1; SMN2 4279/4885CTSK 801/4885
US-20170090287-A1 OVERCOAT COMPOSITIONS AND METHODS FOR PHOTOLITHOGRAPHY OGT, COLGALT1, PARG USP2 717/4885SMN1; SMN2 4742/4885CTSK 1573/4885
US-20170090283-A1 PHOTORESIST COMPOSITIONS AND METHODS PARG, PNN, PARN USP2 2213/4885SMN1; SMN2 4279/4885CTSK 801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.