SCHEMBL18688653

SCHEMBL18688653

c1ccc(-c2ccc3cc(-n4c5ccccc5c5ccc(N(c6ccccc6)c6ccc7c8ccccc8c8ccccc8c7c6)cc54)ccc3c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
TSPO P30536 1/20 0.32
HDAC4 P56524 1/20 0.32
F2 P00734 1/20 0.31
F10 P00742 1/20 0.31
PRSS1 P07477 1/20 0.31
NR3C1 P04150 1/20 0.30
BACE1 P56817 1/20 0.30
FGFR1 P11362 1/20 0.30
DYRK3 O43781 1/20 0.30
CLK1 P49759 1/20 0.30
CLK2 P49760 1/20 0.30
CLK3 P49761 1/20 0.30
GSK3B P49841 1/20 0.30
CDK5 Q00535 1/20 0.30
DYRK1A Q13627 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18688660 0.97 KDM4E (0.35) KDM4EATML3MBTL1ESR1ESR2
SCHEMBL20274779 0.95 KDM4E (0.36) KDM4EATML3MBTL1ESR1ESR2
SCHEMBL18689336 0.93 KDM4E (0.39) KDM4EATML3MBTL1ESR1ESR2
SCHEMBL24374182 0.91 KDM4E (0.37) KDM4EATML3MBTL1ESR1ESR2
SCHEMBL11922071 0.90 KDM4E (0.39) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL20274685 0.90 KDM4E (0.39) KDM4EATML3MBTL1F2F10
SCHEMBL18688709 0.90 L3MBTL1 (0.45) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL20274691 0.90 L3MBTL1 (0.45) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL16158335 0.90 TSPO (0.38) KDM4EATML3MBTL1ESR1ESR2
SCHEMBL14728173 0.90 KDM4E (0.35) KDM4EATML3MBTL1TSPOHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10862045-B2 Amine-based compound and organic light-emitting element comprising same LG CHEM, LTD. 2020-12-08 US disclosed
EP-3336077-B1 AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2019-09-11 EP disclosed
EP-3336077-A2 AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG Chem, Ltd. (KR) 2018-06-20 EP disclosed
WO-2017052138-A2 AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME 주식회사 엘지화학 2017-03-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10862045-B2 Amine-based compound and organic light-emitting element comprising same EML4, OR10J3, AOC2 KDM4E 434/4885ATM 181/4885L3MBTL1 473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.