Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GOT1 | P17174 | 14/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | IDE | P14735 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18690938 | 0.85 | GOT1 (0.47) | GOT1MAPTGAARECQL | |
| SCHEMBL5704805 | 0.81 | GOT1 (0.60) | GOT1MAPTGAARECQLMEN1 | |
| SCHEMBL5704758 | 0.76 | GOT1 (0.56) | GOT1MAPTGAARECQL | |
| SCHEMBL6376236 | 0.74 | ADRB1 (0.60) | GOT1MAPTGAARECQL | |
| SCHEMBL17422030 | 0.74 | AVPR1A (0.38) | GOT1MAPTAVPR1AMEN1IDE | |
| SCHEMBL18690982 | 0.71 | GAA (0.66) | GOT1MAPTGAARECQL | |
| SCHEMBL17738883 | 0.71 | MEN1 (0.41) | GOT1MAPTMEN1IDEKMT2A | |
| SCHEMBL3296720 | 0.68 | GOT1 (0.42) | GOT1MAPTGAARECQLMEN1 | |
| SCHEMBL29182786 | 0.67 | BACE1 (0.46) | GOT1MAPTGAARECQL | |
| SCHEMBL17738876 | 0.67 | MEN1 (0.42) | GOT1MEN1IDEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3166924-B1 | AROMATIC HETEROCYCLIC DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2019-02-20 | — | — | EP | disclosed |
| US-9974785-B2 | Aromatic heterocyclic derivatives and pharmaceutical applications thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2018-05-22 | — | — | US | disclosed |
| US-20170096392-A1 | AROMATIC HETEROCYCLIC DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170096392-A1 | AROMATIC HETEROCYCLIC DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF | HTR6, HTR3A, HTR5A | GOT1 1868/4885MAPT 22/4885GAA 1537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.