Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14948977 | 0.84 | HSD11B1 (0.54) | HSD11B1RAB9ANPC1KMT2ATRPM8 | |
| SCHEMBL14946457 | 0.80 | HSD11B1 (0.51) | HSD11B1RAB9ANPC1KMT2ATRPM8 | |
| SCHEMBL12313813 | 0.79 | HSD11B1 (0.58) | HSD11B1RAB9ANPC1KMT2ATRPM8 | |
| SCHEMBL21120544 | 0.75 | MEN1 (0.55) | RAB9ANPC1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21400129 | 0.75 | HSD11B1 (0.56) | HSD11B1RAB9ANPC1KMT2ATRPM8 | |
| SCHEMBL12265806 | 0.71 | HSD11B1 (0.52) | HSD11B1RAB9ANPC1KMT2ATRPM8 | |
| SCHEMBL6667849 | 0.70 | HSD11B1 (0.51) | HSD11B1RAB9ANPC1KMT2ATRPM8 | |
| SCHEMBL3324146 | 0.68 | HSD11B1 (1.00) | HSD11B1RAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL13600521 | 0.68 | DRD2 (0.42) | HSD11B1RAB9ANPC1KMT2ATRPM8 | |
| SCHEMBL7418944 | 0.67 | TRPM8 (0.45) | HSD11B1RAB9ANPC1KMT2ATRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9609870-B2 | Herbicidal isoxazolo[5,4-b]pyridines | BASF SE (DE) | 2017-04-04 | — | — | US | disclosed |