Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 9/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3349867 | 0.80 | MEN1 (0.40) | CXCR3 | |
| SCHEMBL3993586 | 0.80 | CXCR3 (0.45) | CXCR3HTR7DRD2DRD3HTR1A | |
| SCHEMBL3318467 | 0.71 | HTR7 (0.45) | CXCR3HTR7DRD2DRD3HTR1A | |
| SCHEMBL18723564 | 0.71 | SIGMAR1 (0.40) | DRD3HTR1ASLC6A4 | |
| SCHEMBL23004926 | 0.68 | ACHE (0.68) | HTR7DRD2DRD3HTR1AHTR2A | |
| SCHEMBL18675227 | 0.65 | DRD2 (0.53) | HTR7DRD2DRD3HTR1AHTR2A | |
| SCHEMBL3318873 | 0.65 | CYP1A2 (0.37) | — | |
| SCHEMBL29110825 | 0.65 | CARM1 (0.56) | HTR7DRD2DRD3HTR1AHTR2A | |
| SCHEMBL3246920 | 0.64 | MAOA (0.59) | HTR7DRD3HTR1AHTR2AHTR2B | |
| SCHEMBL13487187 | 0.64 | MAOA (0.59) | HTR7DRD3HTR1AHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066648-B1 | SUBSTITUTED DIMETHYLCYCLOBUTYL COMPOUNDS, THEIR PREPARATION AND USE IN MEDICAMENTS | ESTEVE LABOR DR (ES) | 2017-04-12 | — | — | EP | disclosed |