SCHEMBL1872409

SCHEMBL1872409

O=C1CC(C(F)(F)F)CN1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 1/20 0.31
MAP3K14 Q99558 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30497332 1.00 MTNR1A (0.31) MTNR1AMAP3K14
2-Pyrrolidone SCHEMBL28180594 0.85 OR51E2 (0.52)
Morpholine SCHEMBL28181341 0.84 GAA (0.35)
SCHEMBL1262601 0.77 CRBN (0.36)
SCHEMBL26664053 0.77 CRBN (0.36)
SCHEMBL25324227 0.77 NOS3 (0.35)
SCHEMBL26663291 0.77 CRBN (0.36)
SCHEMBL14592897 0.76 ALDH1A1 (0.34) MTNR1A
SCHEMBL14592820 0.76 ALDH1A1 (0.34) MTNR1A
SCHEMBL8931418 0.76 ALDH1A1 (0.34) MTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9592243-B2 Medical devices and methods comprising an anabolic agent for treatment of an injury WARSAW ORTHOPEDIC, INC. (US) 2017-03-14 US claimed
US-20150320739-A1 Pharmaceutical Compositions for the Treatment of Sexual Disorders II BAUSCH HEALTH IRELAND LIMITED (F/K/A/ VALEANT PHARMACEUTICALS IRELAND LIMITED) (IE) 2015-11-12 US claimed
US-20130203766-A1 Pharmaceutical Compositions for the Treatment of Sexual Disorders II SPROUT PHARMACEUTICALS, INC. (US) 2013-08-08 US claimed
US-20110105519-A1 Pharmaceutical Compositions for the Treatment of Sexual Disorders II SPROUT PHARMACEUTICALS, INC. 2011-05-05 US claimed
CN-101243074-A Heterocyclic compounds JAPAN TOBACCO INC (JP) 2008-08-13 CN claimed
US-20080103155-A1 Pharmaceutical compositions for the treatment of sexual disorders II SPROUT PHARMACEUTICALS, INC. 2008-05-01 US claimed
CN-1946404-A Pharmaceutical compositions for the treatment of sexual disorders II BOEHRINGER INGELHEIM PHARMA (DE) 2007-04-11 CN claimed
EP-1740181-A1 NEW PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF SEXUAL DISORDERS II BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-01-10 EP claimed
US-20050245539-A1 Pharmaceutical compositions for the treatment of sexual disorders II BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-11-03 US claimed
WO-2005102342-A1 NEW PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF SEXUAL DISORDERS II BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-11-03 WO claimed
US-20040044080-A1 Treatment of dyspareunia with topically administered nitroglycerin formulations VIVUS, INC. 2004-03-04 US claimed
EP-4688156-A1 LACTAM-CONTAINING IMIDAZOPYRIDAZINE IL-17 INHIBITOR COMPOUNDS Janssen Pharmaceutica NV (BE) 2026-02-11 EP disclosed
US-20250346602-A1 LACTAM SUBSTITUTED IMIDAZOPYRIDAZINE IL-17A MODULATORS AND USES THEREOF DICE ALPHA INC (US) 2025-11-13 US disclosed
WO-2025072451-A1 RAS-PI3K INHIBITORS FOR THE TREATMENT OF CANCER AND IMMUNOLOGICAL DISEASES VIVIDION THERAPEUTICS, INC. (US) 2025-04-03 WO disclosed
EP-4525987-A1 LACTAM SUBSTITUTED IMIDAZOPYRIDAZINE IL-17A MODULATORS AND USES THEREOF Dice Alpha, Inc. (US) 2025-03-26 EP disclosed
CN-1946404-A Pharmaceutical compositions for the treatment of sexual disorders II BOEHRINGER INGELHEIM PHARMA (DE) 2007-04-11 CN disclosed
EP-1740181-A1 NEW PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF SEXUAL DISORDERS II BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-01-10 EP disclosed
US-20050245539-A1 Pharmaceutical compositions for the treatment of sexual disorders II BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-11-03 US disclosed
WO-2005102342-A1 NEW PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF SEXUAL DISORDERS II BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-11-03 WO disclosed
US-20040044080-A1 Treatment of dyspareunia with topically administered nitroglycerin formulations VIVUS, INC. 2004-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080103155-A1 Pharmaceutical compositions for the treatment of sexual disorders II FLNB, FLNA, FGB MTNR1A 258/4885MAP3K14 3298/4885
US-20250346602-A1 LACTAM SUBSTITUTED IMIDAZOPYRIDAZINE IL-17A MODULATORS AND USES THEREOF IL17A, IL15, IL18 MTNR1A 2835/4885MAP3K14 1361/4885
US-20130203766-A1 Pharmaceutical Compositions for the Treatment of Sexual Disorders II FLNB, FLNA, FGB MTNR1A 258/4885MAP3K14 3298/4885
US-20110105519-A1 Pharmaceutical Compositions for the Treatment of Sexual Disorders II FLNB, FLNA, FGB MTNR1A 258/4885MAP3K14 3298/4885
US-20150320739-A1 Pharmaceutical Compositions for the Treatment of Sexual Disorders II FLNB, FLNA, FGB MTNR1A 258/4885MAP3K14 3298/4885
US-20040044080-A1 Treatment of dyspareunia with topically administered nitroglycerin formulations PDE12, PDE3A, PDE2A MTNR1A 345/4885MAP3K14 975/4885
US-20050245539-A1 Pharmaceutical compositions for the treatment of sexual disorders II FLNB, FLNA, FGB MTNR1A 258/4885MAP3K14 3298/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.