Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18725308 | 0.88 | NR1H2 (0.34) | HTR7DRD2OPRM1OPRD1OPRK1 | |
| SCHEMBL2226221 | 0.80 | OPRM1 (0.35) | OPRM1OPRD1OPRK1 | |
| SCHEMBL2224887 | 0.76 | NR1H2 (0.45) | HTR7DRD2OPRM1NR1H2NR1H3 | |
| SCHEMBL29252729 | 0.67 | AGTR2 (0.48) | DRD2NR1H2NR1H3DRD3 | |
| SCHEMBL11963285 | 0.66 | NR1H2 (0.44) | NR1H2NR1H3 | |
| SCHEMBL2333783 | 0.65 | NR1H2 (0.43) | NR1H2NR1H3 | |
| SCHEMBL674603 | 0.64 | ALOX5 (0.46) | NR1H2NR1H3 | |
| SCHEMBL673259 | 0.64 | NR1H2 (0.51) | NR1H2NR1H3 | |
| SCHEMBL2452095 | 0.63 | SIGMAR1 (0.33) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL18725929 | 0.62 | PRKDC (0.40) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2544535-B1 | PHENOXY THIOPHENE SULFONAMIDES AND THEIR USE AS INHIBITORS OF GLUCURONIDASE | NORTH CAROLINA CENTRAL UNIV (US) | 2017-04-19 | — | — | EP | claimed |