SCHEMBL18740351

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18740013	0.93	CISD2 (0.39)	NOX4LMNAPKMCISD2MEN1
	SCHEMBL18739970	0.86	NOX4 (0.37)	NOX4MEN1KMT2AFPR2ALDH1A1
	SCHEMBL18758538	0.83	PDE2A (0.43)	ALDH1A1CYP2C9
	SCHEMBL18758616	0.83	BRD4 (0.42)	LMNAALDH1A1POLBGAAMAPT
	SCHEMBL18740168	0.82	KDM4E (0.41)	LMNAPKMMEN1KMT2AKDM4E
	SCHEMBL18740275	0.81	LMNA (0.46)	LMNAMEN1KMT2AALDH1A1POLB
	SCHEMBL18740127	0.79	NOTUM (0.39)	MEN1KMT2AFPR2MAPTCCR1
	SCHEMBL18758566	0.77	PTGER4 (0.42)	ALDH1A1CYP2C9
	SCHEMBL18740120	0.77	PTGER4 (0.49)	CYP2C9
	SCHEMBL18740123	0.77	PTGER4 (0.49)	CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.