SCHEMBL187447

SCHEMBL187447

COC(=O)c1ccc(Br)cc1C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.49
GAA P10253 3/20 0.49
ALDH1A1 P00352 3/20 0.49
MAPT P10636 2/20 0.49
HSD17B10 Q99714 2/20 0.49
KDM4E B2RXH2 2/20 0.49
HPGD P15428 2/20 0.49
GLA P06280 1/20 0.49
CASP1 P29466 1/20 0.49
CASP7 P55210 1/20 0.49
ATM Q13315 1/20 0.49
SLC6A3 Q01959 1/20 0.47
CA12 O43570 2/20 0.47
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
CA7 P43166 2/20 0.47
CA9 Q16790 2/20 0.47
CA14 Q9ULX7 2/20 0.47
PDK2 Q15119 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30752935 1.00 NR4A2 (0.53) NR4A2L3MBTL1GAAALDH1A1MAPT
Methane SCHEMBL28799503 0.98 NR4A2 (0.51) NR4A2L3MBTL1GAAALDH1A1MAPT
SCHEMBL30017691 0.85 NR4A2 (0.53) NR4A2L3MBTL1GAAALDH1A1MAPT
SCHEMBL155514 0.85 NR4A2 (0.53) NR4A2L3MBTL1GAAALDH1A1MAPT
SCHEMBL4577829 0.84 NR4A2 (0.56) NR4A2L3MBTL1GAAALDH1A1MAPT
SCHEMBL29773857 0.84 NR4A2 (0.56) NR4A2L3MBTL1GAAALDH1A1MAPT
SCHEMBL3839211 0.82 NR4A2 (0.54) NR4A2L3MBTL1GAAALDH1A1MAPT
SCHEMBL25603748 0.82 SLC6A3 (0.47) NR4A2GAAALDH1A1MAPTHSD17B10
SCHEMBL289045 0.81 ALDH1A1 (0.55) ALDH1A1MAPTHSD17B10CA12CA1
SCHEMBL1378325 0.81 CA12 (0.67) NR4A2L3MBTL1GAAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1386 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115160134-B Preparation method of 4-bromo-2-methyl benzoate 无锡科华生物科技有限公司 2023-10-10 CN claimed
CN-217646394-U A reation kettle for 4-bromo-2-methyl benzoate is synthetic 上海率典医药科技有限公司 2022-10-25 CN claimed
CN-115160134-A Preparation method of 4-bromo-2-methyl benzoate 无锡科华生物科技有限公司 2022-10-11 CN claimed
CN-114015905-B Process for preparing nano-grade zirconium-based non-evaporable getter material 安徽有研吸气材料有限公司 2022-05-10 CN claimed
CN-114015905-A Process for preparing nano-grade zirconium-based non-evaporable getter material 安徽有研吸气材料有限公司 2022-02-08 CN claimed
EP-3692101-B1 BRILLIANT BLUE (BBG) DYE DERIVATIVES AND STAINING COMPOSITIONS COMPRISING THE SAME FOR SELECTIVELY STAINING BIOLOGICAL SUBSTRATES ALFA INSTR S R L (IT) 2022-01-12 EP claimed
CN-113662941-A Antiproliferative compounds and pharmaceutical compositions and uses thereof 细胞基因公司 2021-11-19 CN claimed
CN-109553532-B Preparation method of 4-bromoacetyl-2-methyl benzoic acid methyl ester 荆门医药工业技术研究院 2021-04-02 CN claimed
EP-3692101-A1 BRILLIANT BLUE (BBG) DYE DERIVATIVES AND STAINING COMPOSITIONS COMPRISING THE SAME FOR SELECTIVELY STAINING BIOLOGICAL SUBSTRATES Alfa Instruments S.r.l. (IT) 2020-08-12 EP claimed
WO-2019068935-A1 BRILLIANT BLUE (BBG) DYE DERIVATIVES AND STAINING COMPOSITIONS COMPRISING THE SAME FOR SELECTIVELY STAINING BIOLOGICAL SUBSTRATES ALFA INSTRUMENTS S.R.L. (IT) 2019-04-11 WO claimed
US-12637440-B2 Amide derivative useful as diacylglycerol acyltransferase 2 inhibitor, and use thereof LG CHEM, LTD. (KR) 2026-05-26 US disclosed
WO-2026102082-A1 ALKYLPHENYL SUBSTITUTED COMPOUNDS, COMPOSITIONS AND METHODS OF USE DEEP APPLE THERAPEUTICS, INC. (US) 2026-05-15 WO disclosed
CN-122055152-A Combination therapy of FASN inhibitors with thyroid hormone receptor agonists 萨吉米特生物科学公司 2026-05-15 CN disclosed
US-20260132119-A1 Alkylphenyl Substituted Compounds, Compositions and Methods of Use DEEP APPLE THERAPEUTICS, INC. (US) 2026-05-14 US disclosed
CN-122029148-A N-phenyl-3- (2, 5-dioxopyrrolidin-1-yl) propionamide derivatives and similar compounds as DUX4 inhibitors for the treatment of, for example, neuromuscular diseases 阿勒泰治疗公司 2026-05-12 CN disclosed
WO-1995004716-A1 2-OXIMINOMETHYL-1-PHENYL-1,3-PROPANEDIONE DERIVATIVES AS HERBICIDES RHONE-POULENC AGRICULTURE LTD (GB) 1995-02-16 WO disclosed
EP-0299789-A1 Mesomorphic compound having alkyl beta-hydroxycarboxylate as chiral group and liquid crystal composition containing same MITSUBISHI RAYON CO., LTD. (JP) 1989-01-18 EP disclosed
EP-0069810-B1 NOVEL DIBENZOXEPINS, THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND THE USE OF DIBENZOXEPINS IN THE TREATMENT OF ALLERGIC CONDITIONS MERCK & CO. INC. (US) 1986-12-03 EP disclosed
EP-0069810-A1 Novel dibenzoxepins, their preparation, compositions containing them and the use of dibenzoxepins in the treatment of allergic conditions MERCK & CO. INC. (US) 1983-01-19 EP disclosed
US-4282365-A Dibenz[b,e]oxepin compounds MERCK & CO., INC. (US) 1981-08-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132119-A1 Alkylphenyl Substituted Compounds, Compositions and Methods of Use GIPR, MC2R, GRPR NR4A2 2777/4885L3MBTL1 1493/4885GAA 633/4885
US-12637440-B2 Amide derivative useful as diacylglycerol acyltransferase 2 inhibitor, and use thereof DGAT2, DGAT1, DLAT NR4A2 2151/4885L3MBTL1 991/4885GAA 593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.