SCHEMBL1875012

SCHEMBL1875012

CC(C)(C)N(C(=O)O)c1ccsc1I

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.37
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GLA P06280 1/20 0.35
GAA P10253 1/20 0.35
HPGD P15428 1/20 0.35
MAPK1 P28482 1/20 0.35
AXL P30530 1/20 0.30
RAB9A P51151 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17440232 0.79 LMNA (0.37) LMNAKDM4EALDH1A1GLAGAA
SCHEMBL17440276 0.77 LMNA (0.35) LMNAKDM4EALDH1A1GLAGAA
SCHEMBL28935727 0.76 KDM4E (0.38) LMNAKDM4EALDH1A1GLAGAA
SCHEMBL5743135 0.76 LMNA (0.34) LMNAKDM4EALDH1A1GLAGAA
SCHEMBL1703670 0.71 PKM (0.45) LMNAHPGDRAB9A
SCHEMBL4410432 0.71 LMNA (0.31) LMNAKDM4EALDH1A1GLAGAA
SCHEMBL1703757 0.70 HPGD (0.48) LMNAKDM4EALDH1A1GAAHPGD
SCHEMBL2432062 0.70 FSCN1 (0.39) KDM4EALDH1A1GAAMAPK1L3MBTL1
SCHEMBL1704450 0.69 PKM (0.49) LMNAKDM4EALDH1A1GAARAB9A
SCHEMBL29048373 0.68 DAO (0.39) LMNAALDH1A1GAARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115611895-A Arylamino derivative estrogen receptor modulators and uses thereof 四川海思科制药有限公司 2023-01-17 CN disclosed
US-20110105564-A1 THIENYLPYRIDYLCARBOXAMIDES BAYER CROPSCIENCE AG (DE) 2011-05-05 US disclosed
EP-1965640-A2 THIENYLPYRIDYL CARBOXAMIDES Bayer CropScience AG (DE) 2008-09-10 EP disclosed
WO-2007068374-A2 THIENYLPYRIDYL CARBOXAMIDES BAYER CROPSCIENCE AG (DE) 2007-06-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110105564-A1 THIENYLPYRIDYLCARBOXAMIDES TPI1, PGLS, TYMS LMNA 4290/4885KDM4E 1321/4885ALDH1A1 444/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.