Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 6/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10131420 | 0.79 | ALDH1A1 (0.44) | LTA4HPARP1SIGMAR1SMN1; SMN2SLC2A1 | |
| SCHEMBL3271284 | 0.78 | SIGMAR1 (0.48) | LTA4HPARP1SIGMAR1SMN1; SMN2SLC2A1 | |
| Hydrochloric Acid SCHEMBL18229943 | 0.78 | ALDH1A1 (0.42) | LTA4HPARP1SIGMAR1SMN1; SMN2SLC2A1 | |
| SCHEMBL18461234 | 0.73 | PARP1 (0.38) | LTA4HPARP1SIGMAR1SMN1; SMN2SLC2A1 | |
| SCHEMBL13164692 | 0.72 | ALDH1A1 (0.49) | LTA4HPARP1SIGMAR1SMN1; SMN2SLC2A1 | |
| SCHEMBL8851013 | 0.70 | SMN1; SMN2 (0.58) | LTA4HPARP1SIGMAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3440308 | 0.70 | LOXL2 (0.50) | LTA4HPARP1SIGMAR1SMN1; SMN2SLC2A1 | |
| SCHEMBL8443205 | 0.70 | LMNA (0.48) | LTA4HPARP1SIGMAR1SMN1; SMN2SLC2A1 | |
| SCHEMBL24999530 | 0.69 | SIGMAR1 (0.41) | LTA4HPARP1SIGMAR1SMN1; SMN2SLC2A1 | |
| SCHEMBL14438280 | 0.69 | IDO1 (0.52) | LTA4HPARP1SIGMAR1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3156410-A1 | POLYENE MACROLIDE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2017-04-19 | — | — | EP | disclosed |