Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18768442 | 0.88 | PKM (0.39) | AKR1C3KDM4EDRD2DRD4DRD3 | |
| SCHEMBL18768630 | 0.88 | KDM4E (0.40) | CXCR6AKR1C3KDM4EALDH1A1 | |
| SCHEMBL18768626 | 0.86 | MEN1 (0.46) | MEN1KMT2AAKR1C3 | |
| SCHEMBL18768441 | 0.86 | USP2 (0.47) | MEN1KMT2A | |
| SCHEMBL18768445 | 0.85 | PDGFRB (0.44) | MEN1KMT2AFLT3DRD2DRD3 | |
| SCHEMBL18768577 | 0.84 | DRD2 (0.43) | DRD2DRD1DRD4HTR2CDRD3 | |
| SCHEMBL18768444 | 0.83 | MDM2 (0.50) | DRD2DRD1DRD4HTR2CDRD3 | |
| SCHEMBL18768315 | 0.83 | L3MBTL1 (0.47) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL18768451 | 0.81 | MDM2 (0.44) | DRD2DRD1DRD4HTR2CDRD3 | |
| SCHEMBL18768632 | 0.81 | ALDH1A1 (0.43) | MEN1KMT2ADRD2DRD1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017066705-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE AGAINST STRESS GRANULES | AQUINNAH PHARMACEUTICALS, INC. (US) | 2017-04-20 | — | — | WO | disclosed |