SCHEMBL1877216

SCHEMBL1877216

CC[C@@H](C(=O)O)N1CCCC1=O

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.75
CA12 O43570 1/20 0.75
CA1 P00915 1/20 0.75
CA2 P00918 1/20 0.75
CA3 P07451 1/20 0.75
CA4 P22748 1/20 0.75
CA6 P23280 1/20 0.75
CA5A P35218 1/20 0.75
CA7 P43166 1/20 0.75
CA9 Q16790 1/20 0.75
CA13 Q8N1Q1 1/20 0.75
CA14 Q9ULX7 1/20 0.75
CA5B Q9Y2D0 1/20 0.75
CHRM2 P08172 2/20 0.43
CHRM4 P08173 2/20 0.43
CHRM5 P08912 2/20 0.43
CHRM1 P11229 2/20 0.43
CHRM3 P20309 2/20 0.43
ACE P12821 1/20 0.39
PIK3CD O00329 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2079098 1.00 LMNA (0.75) LMNACA12CA1CA2CA3
SCHEMBL1747843 1.00 LMNA (0.75) LMNACA12CA1CA2CA3
SCHEMBL4942841 0.86 LMNA (0.61) LMNACA12CA1CA2CA3
SCHEMBL19139156 0.86 LMNA (0.61) LMNACA12CA1CA2CA3
SCHEMBL13788532 0.86 LMNA (0.75) LMNACA12CA1CA2CA3
Levetiracetam SCHEMBL118843 0.86 LMNA (1.00) LMNACA12CA1CA2CA3
SCHEMBL13788510 0.86 LMNA (0.75) LMNACA12CA1CA2CA3
Etiracetam SCHEMBL373194 0.86 LMNA (1.00) LMNACA12CA1CA2CA3
Levetiracetam SCHEMBL5072485 0.86 LMNA (1.00) LMNACA12CA1CA2CA3
Levitiracetam SCHEMBL61493 0.86 LMNA (1.00) LMNACA12CA1CA2CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4284778-B1 METHOD FOR PREPARING LEVETIRACETAM AND INTERMEDIATES THEREOF SUZHOU BRIGHTHOPE PHARMATECH CO LTD (CN) 2025-12-17 EP claimed
CN-119569722-A Compound, preparation method and application of compound in treatment of Alzheimer's disease 河南中医药大学 2025-03-07 CN claimed
CN-118390079-A Method for preparing (S) -2- (2-oxo-pyrrolidine-1-yl) butyric acid by electrocatalytic oxidation of volcanic nano-carbon loaded platinum catalyst 衢州市浙工大生态工业创新研究院 2024-07-26 CN claimed
CN-117677605-A Process for preparing levetiracetam and intermediates thereof 维生源知识产权有限责任公司 2024-03-08 CN claimed
CN-113272275-B Preparation method of levetiracetam intermediate 浙江华海药业股份有限公司 2024-01-12 CN claimed
EP-4284778-A1 METHOD FOR PREPARING LEVETIRACETAM AND INTERMEDIATES THEREOF Vitaworks IP, LLC (US) 2023-12-06 EP claimed
CN-116837047-A Method for preparing (S) -alpha-ethyl-2-oxo-1-pyrrolidine acetic acid 浙江华海药业股份有限公司 2023-10-03 CN claimed
CN-110914239-B Method for preparing levetiracetam 浙江华海药业股份有限公司 2023-07-25 CN claimed
CN-115734964-A Preparation method of levetiracetam intermediate 浙江华海药业股份有限公司 2023-03-03 CN claimed
US-20220324801-A1 METHOD FOR PREPARING LEVETIRACETAM AND INTERMEDIATES THEREOF VITAWORKS IP, LLC 2022-10-13 US claimed
US-7902380-B2 Process for the preparation of (S)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide and (R)-alpha-ethyl-2-oxo-pyrrolidineacetamide APOTEX PHARMACHEM INC. (CA) 2011-03-08 US claimed
US-20100076204-A1 PROCESS FOR THE PREPARATION OF LEVETIRACETAM ZACH SYSTEM S.P.A. (IT) 2010-03-25 US claimed
EP-2147911-A1 Process for the preparation of levetiracetam ZaCh System S.p.A. (IT) 2010-01-27 EP claimed
WO-2009057137-A2 A PROCESS FOR THE PURIFICATION OF LEVETIRACETAM ALEMBIC LIMITED (IN) 2009-05-07 WO claimed
EP-2049476-A1 PROCESS FOR THE PREPARATION OF LEVETIRACETAM ZaCh System S.p.A. (IT) 2009-04-22 EP claimed
US-20090069575-A1 Process For The Preparation Of (S)-Alpha-Ethyl-2-Oxo-1-Pyrrolidineacetamide And (R)- Alpha-Ethyl-2-Oxo-Pyrrolidineacetamide APOTEX PHARMACHEM INC. (CA) 2009-03-12 US claimed
WO-2008012268-A1 PROCESS FOR THE PREPARATION OF LEVETIRACETAM ZACH SYSTEM S.P.A. (IT) 2008-01-31 WO claimed
WO-2006127300-A1 SYNTHESIS OF (S)-α-ETHYL-2-OXO-1-PYRROLIDINEACETAMIDE CAMBREX CHARLES CITY, INC. (US) 2006-11-30 WO claimed
US-4943639-A (S)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide U C B SOCIETE ANONYME (BE) 1990-07-24 US claimed
EP-0162036-B1 (S)-ALPHA-ETHYL-2-OXO-1-PYRROLIDINACETAMIDE U C B, S.A. (BE) 1989-08-16 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100076204-A1 PROCESS FOR THE PREPARATION OF LEVETIRACETAM EPM2A, PEPD, ALDH18A1 LMNA 2513/4885CA12 1435/4885CA1 155/4885
US-20090069575-A1 Process For The Preparation Of (S)-Alpha-Ethyl-2-Oxo-1-Pyrrolidineacetamide And (R)- Alpha-Ethyl-2-Oxo-Pyrrolidineacetamide RPS4X, BRIX1, RIOX2 LMNA 3526/4885CA12 1708/4885CA1 846/4885
US-20220324801-A1 METHOD FOR PREPARING LEVETIRACETAM AND INTERMEDIATES THEREOF CS, OTC, SDHA LMNA 576/4885CA12 66/4885CA1 12/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.