Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 6/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.38 |
| ▸ | CLK2 | P49760 | 3/20 | 0.38 |
| ▸ | CLK3 | P49761 | 3/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 8/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18790687 | 0.80 | CYP11B2 (0.49) | CYP11B2RAD52DYRK1APIM2PIM1 | |
| SCHEMBL18790698 | 0.78 | CYP11B2 (0.56) | CYP11B2DYRK1ACLK2CLK3PIM2 | |
| SCHEMBL18790696 | 0.69 | CYP11B2 (0.61) | CYP11B2RAD52DYRK1APIM2PIM1 | |
| SCHEMBL18790991 | 0.67 | CYP11B2 (0.90) | CYP11B2DYRK1APIM2PIM1CSNK2A2 | |
| SCHEMBL18791085 | 0.66 | CYP11B2 (0.73) | CYP11B2 | |
| SCHEMBL18790685 | 0.63 | PIM2 (0.48) | CYP11B2RAD52DYRK1APIM2PIM1 | |
| SCHEMBL22236836 | 0.61 | CYP11B2 (0.58) | CYP11B2 | |
| SCHEMBL18790689 | 0.61 | CYP11B2 (0.44) | CYP11B2RAD52DYRK1ACLK2CLK3 | |
| SCHEMBL20514041 | 0.61 | CYP11B2 (0.68) | CYP11B2DYRK1A | |
| SCHEMBL18790990 | 0.60 | ALDH1A1 (0.52) | CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017069226-A1 | NOVEL NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND | 田辺三菱製薬株式会社 | 2017-04-27 | — | — | WO | disclosed |