SCHEMBL187920

SCHEMBL187920

O=CCCCCCCCCCCCCO

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.53
TSHR P16473 3/20 0.52
FAAH O00519 2/20 0.46
TRPV1 Q8NER1 2/20 0.46
GPR84 Q9NQS5 1/20 0.39
FFAR1 O14842 1/20 0.39
FFAR4 Q5NUL3 1/20 0.39
LMNA P02545 2/20 0.38
ALDH1A1 P00352 2/20 0.38
HSD17B10 Q99714 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.33
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.31
CAMK2A Q9UQM7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10451601 1.00 HIF1A (0.53) HIF1ATSHRFAAHTRPV1GPR84
SCHEMBL1958540 1.00 HIF1A (0.53) HIF1ATSHRFAAHTRPV1GPR84
SCHEMBL3089090 1.00 HIF1A (0.53) HIF1ATSHRFAAHTRPV1GPR84
SCHEMBL13287154 1.00 HIF1A (0.53) HIF1ATSHRFAAHTRPV1GPR84
SCHEMBL973120 1.00
SCHEMBL19816822 1.00 HIF1A (0.53) HIF1ATSHRFAAHTRPV1GPR84
1,6-Hexanediol SCHEMBL8450098 1.00 HIF1A (0.53) HIF1ATSHRFAAHTRPV1GPR84
SCHEMBL1958838 1.00 HIF1A (0.53) HIF1ATSHRFAAHTRPV1GPR84
SCHEMBL9407145 1.00
SCHEMBL2458519 1.00 HIF1A (0.53) HIF1ATSHRFAAHTRPV1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 348 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117898291-A Poplar plutella xylostella sex pheromone antagonist and application thereof 中国林业科学研究院森林生态环境与自然保护研究所(国家林业和草原局世界自然遗产保护研究中心) 2024-04-19 CN claimed
EP-2401335-B1 COATINGS AND PRINTING INK COMPOSITIONS CONTAINING SILYLATED POLYETHER SURFACTANTS AND ARTICLES MADE THEREFROM MOMENTIVE PERFORMANCE MAT INC (US) 2018-08-01 EP claimed
EP-3333171-A1 FLUORINE-FREE TRISILOXANE SURFACTANT COMPOSITIONS FOR USE IN COATINGS Momentive Performance Materials Inc. (US) 2018-06-13 EP claimed
EP-2086987-B1 FLUORINE-FREE TRISILOXANE SURFACTANT COMPOSITIONS FOR USE IN PRINTING INK COMPOSITIONS MOMENTIVE PERFORMANCE MAT INC (US) 2018-04-18 EP claimed
CN-102405265-B Coating and printing ink compositions comprising silylated polyether surfactants and articles made therefrom 莫门蒂夫性能材料股份有限公司 2016-06-15 CN claimed
CN-101370378-B Extreme environment surfactant compositions comprising hydrolysis resistant organomodified disiloxane surfactants MOMENTIVE PERFORMANCE MAT INC 2015-03-11 CN claimed
CN-101917844-B Use of hydrolysis resistant organomodified silylated surfactants MOMENTIVE PERFORMANCE MAT INC 2015-02-18 CN claimed
CN-102317391-B Silane coating compositions containing silicon-based polyether copolymers, methods for coating metal surfaces and articles made therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2014-10-15 CN claimed
CN-103396693-A Fluorine-free trisiloxane surfactant composition for use in coating and printing ink composition GEN ELECTRIC 2013-11-20 CN claimed
EP-2311843-B1 Compositions comprising hydrolysis-resistant organomodified silylated surfactants MOMENTIVE PERFORMANCE MAT INC (US) 2013-07-31 EP claimed
WO-2008048593-A2 FLUORINE-FREE TRISILOXANE SURFACTANT COMPOSITIONS FOR USE IN COATINGS AND PRINTING INK COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-04-24 WO claimed
US-20080090963-A1 Fluorine-free trisiloxane surfactant compositions for use in coatings and printing ink compositions GENERAL ELECTRIC COMPANY (US) 2008-04-17 US claimed
US-20080090964-A1 Fluorine-free disiloxane surfactant compositions for use in coatings and printing ink compositions GENERAL ELECTRIC COMPANY (US) 2008-04-17 US claimed
WO-2007139615-A2 USE OF HYDROLYSIS RESISTANT ORGANOMODIFIED SILYLATED SURFACTANTS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2007-12-06 WO claimed
US-20070269467-A1 Use of hydrolysis resistant organomodified silylated surfactants MOMENTIVE PERFORMANCE MATERIALS INC. 2007-11-22 US claimed
WO-2007089330-A2 EXTREME ENVIRONMENT SURFACTANT COMPOSITIONS COMPRISING HYDROLYSIS RESISTANT ORGANOMODIFIED DISILOXANE SURFACTANTS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2007-08-09 WO claimed
WO-2007070469-A2 EXTREME ENVIRONMENTAL SURFACTANT COMPOSITIONS COMPRISING HYDROLYSIS RESISTANT ORGANOMODIFIED DISILOXANE SURFACTANTS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2007-06-21 WO claimed
US-20070135308-A1 Extreme environment surfactant compositions comprising hydrolysis resistant organomodified disiloxane surfactants GENERAL ELECTRIC COMPANY 2007-06-14 US claimed
US-20070087937-A1 EXTREME ENVIRONMENT SURFACTANT COMPOSITIONS COMPRISING HYDROLYSIS RESISTANT ORGANOMODIFIED DISILOXANE SURFACTANTS MOMENTIVE PERFORMANCE MATERIALS INC. 2007-04-19 US claimed
US-5880075-A ESTER ADDITIVES OF SPECIFIED ACIDS AND ALCOHOLS EXXON CHEMICAL PATENTS INC (US) 1999-03-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070087937-A1 EXTREME ENVIRONMENT SURFACTANT COMPOSITIONS COMPRISING HYDROLYSIS RESISTANT ORGANOMODIFIED DISILOXANE SURFACTANTS HDHD5, P4HB, MCM6 HIF1A 2278/4885TSHR 2050/4885FAAH 645/4885
US-20070269467-A1 Use of hydrolysis resistant organomodified silylated surfactants CEL, LCT, SI HIF1A 4672/4885TSHR 1146/4885FAAH 147/4885
US-20070135308-A1 Extreme environment surfactant compositions comprising hydrolysis resistant organomodified disiloxane surfactants MSR1, HDHD5, TPD52L2 HIF1A 2864/4885TSHR 803/4885FAAH 1511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.