Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18796007 | 0.85 | NPSR1 (0.41) | L3MBTL1HSPB1ALDH1A1TDP1HTT | |
| SCHEMBL18796408 | 0.80 | HTT (0.47) | L3MBTL1HSPB1ALDH1A1HPGDTDP1 | |
| SCHEMBL21858445 | 0.79 | NPSR1 (0.46) | ALDH1A1HPGDTDP1HTTMAPT | |
| SCHEMBL18796251 | 0.79 | LMNA (0.39) | ALDH1A1HPGDHTTMAPTPOLB | |
| SCHEMBL21195829 | 0.78 | AMY1A (0.37) | HSPB1ALDH1A1TDP1HTTMAPT | |
| SCHEMBL26440720 | 0.77 | PDE2A (0.34) | ALDH1A1HTTMAPTPOLBLMNA | |
| SCHEMBL18795921 | 0.77 | L3MBTL1 (0.54) | L3MBTL1HSPB1ALDH1A1HPGDTDP1 | |
| SCHEMBL18796108 | 0.76 | LMNA (0.32) | ALDH1A1HTTMAPTPOLBLMNA | |
| SCHEMBL18796130 | 0.76 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL18796008 | 0.75 | ALDH1A1 (0.32) | ALDH1A1HTTMAPTPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108349897-B | Trisubstituted silylphenoxyheterocycles and analogs | 拜耳作物科学股份公司 | 2022-03-04 | — | — | CN | disclosed |
| EP-3368514-B1 | TRISUBSTITUTED SILYLPHENOXYHETEROCYCLES AND ANALOGUES | BAYER CROPSCIENCE AG (DE) | 2021-08-18 | — | — | EP | disclosed |
| US-10683311-B2 | Trisubstitutedsilylphenoxyheterocycles and analogues | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-06-16 | — | — | US | disclosed |
| US-20190233444-A1 | TRISUBSTITUTEDSILYLPHENOXYHETEROCYCLES AND ANALOGUES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-08-01 | — | — | US | disclosed |
| EP-3368514-A1 | TRISUBSTITUTEDSILYLPHENOXYHETEROCYCLES AND ANALOGUES | Bayer CropScience Aktiengesellschaft (DE) | 2018-09-05 | — | — | EP | disclosed |
| WO-2017072283-A1 | TRISUBSTITUTEDSILYLPHENOXYHETEROCYCLES AND ANALOGUES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10683311-B2 | Trisubstitutedsilylphenoxyheterocycles and analogues | PIK3C3, ERG28, DDT | L3MBTL1 2453/4885HSPB1 3905/4885ALDH1A1 3139/4885 |
| US-20190233444-A1 | TRISUBSTITUTEDSILYLPHENOXYHETEROCYCLES AND ANALOGUES | PIK3C3, ERG28, DDT | L3MBTL1 2453/4885HSPB1 3905/4885ALDH1A1 3139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.