Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL741984 | 0.89 | POLB (0.47) | TYMP | |
| SCHEMBL780047 | 0.89 | TK1 (0.49) | TYMPTYMS | |
| SCHEMBL780058 | 0.87 | TYMP (0.44) | TYMPTYMS | |
| SCHEMBL25414279 | 0.87 | TYMS (0.44) | TYMPTYMS | |
| SCHEMBL3568613 | 0.85 | DUT (0.53) | TYMPTYMS | |
| SCHEMBL781015 | 0.76 | — | — | |
| SCHEMBL3066188 | 0.75 | TYMP (0.57) | TYMPTYMS | |
| SCHEMBL3066187 | 0.75 | TYMP (0.57) | TYMPTYMS | |
| SCHEMBL6316914 | 0.75 | RNASE1 (0.42) | — | |
| SCHEMBL1727320 | 0.74 | POLB (0.58) | TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809357-B2 | Compounds and derivatizations of DNAs and RNAs on the nucleobases of pyrimidines for function, structure and therapeutics | HUANG, ZHEN, DR. | 2014-08-19 | — | — | US | disclosed |
| US-20120070825-A1 | Novel Compounds and Derivatizations of DNAs and RNAs on the Nucleobases of Pyrimidines for Function, Structure and Therapeutics | SENA RESEARCH, INC. (US) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120070825-A1 | Novel Compounds and Derivatizations of DNAs and RNAs on the Nucleobases of Pyrimidines for Function, Structure and Therapeutics | NSUN2, RNMT, TRDMT1 | TYMP 14/4885TYMS 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.