SCHEMBL187989

SCHEMBL187989

CC(C)(C)c1ccc(C(C)(OP(O)F)c2ccc(C(C)(C)C)cc2C(C)(C)C)c(C(C)(C)C)c1

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
PKM P14618 1/20 0.33
RECQL P46063 1/20 0.33
KMT2A Q03164 1/20 0.33
ACLY P53396 1/20 0.33
ACHE P22303 3/20 0.33
LMNA P02545 1/20 0.31
TYR P14679 1/20 0.31
NR1I2 O75469 1/20 0.31
KIF11 P52732 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2318110 0.86 ALDH1A1 (0.34) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL8390717 0.86 ALDH1A1 (0.38) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL6400018 0.85 ALDH1A1 (0.35) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL9356123 0.83 SMN1; SMN2 (0.37) ALDH1A1MAPTTYR
SCHEMBL9328182 0.83 ALDH1A1 (0.36) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL1406188 0.80 CA2 (0.42) ALDH1A1ALOX15TDP1MEN1GAA
SCHEMBL10414666 0.80 CNR2 (0.39)
SCHEMBL9356082 0.80 HSPA5 (0.37) ALDH1A1MEN1MAPTKMT2A
SCHEMBL10414674 0.79 ESR1 (0.31) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL10414640 0.77 SHBG (0.40) ALDH1A1HSD17B10MEN1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 497 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6391949-B1 None US claimed
US-6800676-B2 ULTRAVIOLET RADIATION ABSORBERS; HEAT AND OXIDATION RESISTANCE CIBA SPECIALTY CHEMICALS CORPORATION 2004-10-05 US claimed
US-6800678-B2 A SYNERGISTIC MIXTURE OF A HINDERED AMINE BASED ON A (1-ALKOXY-2,2,6,6-TETRAALKYLPIPERIDIN-4-YL)-CONTAINING COMPOUND AND AN ORGANIC OR INORGANIC BROMINATED- AND/OR PHOSPHORUS-CONTAINING FLAME RETARDANT; POLYPROPYLENE CIBA SPECIALTY CHEMICALS CORPORATION 2004-10-05 US claimed
EP-1131483-B1 INHIBITION OF PULP AND PAPER YELLOWING USING HYDROXYLAMINES AND OTHER COADDITIVES CIBA SC HOLDING AG (CH) 2003-11-05 EP claimed
US-20030149143-A1 Flame retardant compositions HORSEY DOUGLAS WAYNE (US) 2003-08-07 US claimed
US-6599326-B1 Composition having reduced loss of brightness and enhanced resistance to yellowing which comprises chemical paper which may still contain traces of lignin and N,N-dialkylhydroxylamine or derivative or salt thereof CIBA SPECIALTY CHEMICALS CORPORATION 2003-07-29 US claimed
US-6599963-B2 Polymer substrate, and a synergistic mixture of a hindered amine and a phosphorus or bromine compound. CIBA SPECIALTY CHEMICALS CORPORATION 2003-07-29 US claimed
US-20030130384-A1 Flame retardant compositions HORSEY DOUGLAS WAYNE (US) 2003-07-10 US claimed
US-20030120077-A1 Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES PETER (US) 2003-06-26 US claimed
EP-0905180-B1 Dust free stabiliser granules containing epoxide and process of their preparation CIBA SC HOLDING AG (CH) 2003-05-21 EP claimed
EP-0416321-B1 Crystalline polyolefin composition CHISSO CORP (JP) 1994-11-09 EP claimed
US-5356964-A Containing hindered phenol, acrylate compound, organic phosphorus compound, hindered piperidine compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-10-18 US claimed
EP-0280938-B1 Antioxidant aromatic fluorophosphites ETHYL CORP (US) 1994-06-15 EP claimed
EP-0301355-B1 Aqueous aryl fluorophosphite suspension ETHYL CORP (US) 1993-12-29 EP claimed
EP-0530984-A1 Stabilized polyolefin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-03-10 EP claimed
WO-1992004404-A2 THERMOOXIDATIVE STABILIZATION OF POLYOLEFINS WITH AN OXO-PIPERAZINYL-TRIAZINE AND A PHOSPHOROUS ACID ESTER THE B.F. GOODRICH COMPANY (US) 1992-03-19 WO claimed
US-5063264-A Molding materials CHISSO CORPORATION (JP) 1991-11-05 US claimed
EP-0416321-A1 Crystalline polyolefin composition Chisso Corporation (JP) 1991-03-13 EP claimed
US-4958034-A DISCOLORATION INHIBITION; REACTION OF OLEFIN AND MALEIC ANHYDRIDE IN ARYLFLUOROPHOSPHITE PRESENCE ETHYL CORPORATION (US) 1990-09-18 US claimed
US-4912155-A Containing substituted aryl group ETHYL CORPORATION (US) 1990-03-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030120077-A1 Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith OGG1, POLH, OGFOD1 ALDH1A1 825/4885HPGD 1323/4885ALOX15 830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.